Reproductive Health Protection Program


It is the policy of the University of Nevada, Reno to minimize human reproductive health risks that are associated with University laboratories.

Responsible Authority

Vice President for Research and Innovation; Environmental Health & Safety Department (EH&S).


This policy applies to all University employees, students and volunteers who work in University owned or leased laboratories, or laboratory-support storerooms where biological, chemical, or physical reproductive health hazards are present.


Many biological agents and hazardous chemicals that are used in laboratories are recognized as reproductive health hazards (see Appendix I for an example list of known or suspected reproductive hazards). Reproductive health hazards are of particular concern in cases of pregnancy, evaluation or treatment of infertility, or for preconception purposes. This policy describes the University reproductive health protection program applicable to university laboratories, both research and academic teaching laboratories. This policy covers biological, chemical, and physical reproductive hazards with specific guidance on ionizing radiation contained in the University’s Radiation Safety Manual.

Reference Regulations

29 CFR 1910.1200 (OSHA), Hazard Communication

29 CFR 1910.1450 (OSHA), Occupational Exposure to Hazardous Chemicals in Laboratories


Reproductive Hazard

Biological or chemical agent, or physical stressor, that affects the reproductive capabilities of males or females, including chromosomal damage (mutations) and effects on fetuses (teratogens). Biological and chemical agents identified by Safety Data Sheets (SDSs) or other commonly accepted hazard information as producing reproductive effects are considered reproductive hazards.

Laboratory Supervisor

Person who has been assigned responsibility for a particular laboratory space or activity. For research laboratories the supervisor is the principal investigator (PI), and for teaching laboratories the supervisor is the instructor of record.


Deans, Department Chairs, and Directors

Ensure that all principal investigators and laboratory supervisors are aware of the responsibilities and procedures contained in this policy and provide administrative support for implementation of this policy.

Deans are responsible fro approving reproductive health accommodation requests that are not within the scope of the Americans With Disabilities Act and making a final determination regarding accommodation requests when the laboratory supervisor has determined that accommodation is not reasonable.

Laboratory Supervisors and Laboratory Instructors

Identify recognized reproductive health hazards that are present in the laboratory or associated with laboratory work, and implement control methods to reduce personnel exposures to accepted safe levels.

Communicate information to laboratory personnel regarding reproductive hazards in the laboratory, to include the identity of reproductive hazards and the methods to be used to limit personnel exposures to accepted safe levels.

Implement appropriate engineered controls, safe work practices, and use of personal protective equipment so that personnel exposures to reproductive hazards are reduced to accepted safe levels, with the goal of eliminating reproductive hazards where feasible.

Upon receiving a Reproductive Health Declaration, ensure that provisions of this policy are carried out, to include review of reproductive health hazards and implementation of recommended exposure control methods and approved accommodations.

Laboratory instructors are responsible for completing a Reproductive Health Hazard Questionnaire for reproductive health declarations made by a student due to exposure to reproductive health hazards in an instructional laboratory class.

Laboratory Employees, Students, and Volunteers

As desired, declare pregnancy, preconception, or evaluation or treatment of infertility by submitting a Reproductive Health Declaration to Human Resources. If accommodation will be requested, complete the applicable section of the Reproductive Health Declaration form.

Once a reproductive health hazard declaration is made, the declaring individual is responsible for submitting a Reproductive Health Hazard Questionnaire to EH&S.

Human Resources

Provide consultation to the laboratory supervisor or instructor, and the responsible chair, director, or dean regarding work assignments and accommodations recommended by the declaring person’s personal physician or EH&S, or when requested by the declaring individual.

Environmental Health and Safety

Upon request, provide advice and service related to reproductive health risks, to include: 1) identification of reproductive health hazards, 2) exposure monitoring, 3) risk assessment, 4) methods to lower risks, and 5) information and training.


Declaration of Pregnancy, Preconception, or Evaluation or Treatment of Infertility, and Request for Accommodation

  1. The individual who wants to declare their pregnancy, intent to conceive, or evaluation or treatment of infertility must submit a completed Reproductive Health Declaration Form (Appendix II) to the Human Resources Department (HR) at MS 0240.
  2. If the declared individual wants to request a reproductive health accommodation, he or she must make this request by completing the applicable portion of the Reproductive Health Declaration Form.
  3. HR will promptly forward a copy of the declaration form to the laboratory supervisor or instructor, and EH&S. If it appears to HR that the Americans With Disabilities Act may apply to the request, the declaration form shall also be forwarded to the Equal Opportunity/Title IX Office (EO/TIX Office) for consideration if the declarant is an employee, or to the Disability Resource Center (DRC) if the declarant is a student.
  4. If an accommodation was requested, HR will contact the laboratory supervisor or supervisor to discuss the request. If the requested accommodation is determined to be reasonable, the accommodation should be provided, with the approval of the responsible dean, unless the request falls under the scope of the Americans With Disabilities Act, which request will then be evaluated by the EO/TIX Office and the Accommodation Committee, or by the DRC as necessary. If the laboratory supervisor, instructor, Accommodation Committee, or DRC determines that the request is not reasonable, or not allowable due to grant funding restrictions, the accommodation request will be forwarded to the responsible dean for a final decision.
  5. Any accommodation for an employee must be a documented agreement between the affected person and their supervisor, with approval by the dean, and HR. The documentation should include an outline of temporary assignments and effective time periods and be signed by the declaring person, the laboratory supervisor or instructor; the dean; and HR representative.

Review of Reproductive Hazards

  1. If the declaring individual is an employee or volunteer he or she will complete the entire Reproductive Health Hazard Questionnaire (Appendix III) and submit it to EH&S. If the individual is declaring only as a student in an instructional laboratory class, he or she will complete only Section I of the questionnaire before submitting it to EH&S. If the individual is making a declaration as an employee/volunteer and as a student, he or she will submit multiple questionnaires, one for the research laboratory in which they work, and one for each academic instructional laboratory in which they are an enrolled student.
  2. When EH&S receives a questionnaire from a student, the questionnaire will be forwarded to the responsible laboratory instructor, who will complete Section II and return the questionnaire to EH&S.
  3. EH&S completes a reproductive health risk evaluation of the work area based on the completed questionnaire and a review of laboratory operations. EH&S provides a copy of the evaluation and any recommendations for reducing exposures to reproductive hazards to the declaring individual and the laboratory supervisor or instructor.
  4. The laboratory supervisor or instructor, EH&S representative, and the declaring individual will meet to review the questionnaire and evaluation.

Physician Review

  1. The declaring individual is encouraged to share the EH&S evaluation with his or her personal physician. The declaring individual is also encouraged to provide a copy of any work restrictions recommended by the personal physician to the laboratory supervisor. The physician’s recommended work restrictions must not include any personal medical information.
  2. The laboratory supervisor forwards any recommended work restrictions provided by the physician to HR and EH&S. If the laboratory supervisor has any questions about implementing the work restrictions he or she should consult with HR and EH&S as appropriate.

Related Documents

University Chemical Hygiene Plan

University Hazard Communication Program

University Radiation Safety Manual


  1. American College of Occupational and Environmental Medicine (1994) ACOEM Reproductive and Developmental Hazard Management Guidelines, Journal of Occupational and Environmental Medicine, January 1996, Volume 33, issue 1, pp. 83 – 90.

Appendix I: Examples of Known or Suspected Reproductive Hazards

The following list provides examples of biological, chemical, and physical agents that have been implicated as reproductive hazards. This list is intended as a guide, and is not inclusive. For more information on reproductive hazards review Safety Data Sheets and other sources of biological and chemical hazard information, or contact EH&S at (775) 327-5040.

Biological Agents


  • Arenaviruses (Hemorrhagic fever, Lasa fever)
  • Cytomegalovirus
  • Filoviruses (Marburg virus, Ebola virus)
  • Hepatitis B virus
  • Hepatitis C virus
  • Herpes simplex virus
  • Human immunodeficiency virus (HIV-1)
  • Measles virus
  • Mumps virus
  • Parvovirus B19
  • Rubella virus
  • Varicella-zoster virus


  • Borrelia burgdorferi (Lyme disease)
  • Campylobacter sp.
  • Chlamydia psitaci (psittacosis)
  • Chlamydia trachomatis
  • Clostridium perfringens
  • Listeria monocytogenes
  • Mycobacterium tuberculosis
  • Mycobacterium leprae
  • Neisseria gonorrhoeae
  • Pasteurella multocida
  • Borrelia sp. (relapsing fever)
  • Salmonella sp.
  • Treponema pallidum


  • Blastomyces dermatitidis (blastomycosis)


  • Plasmodium sp. (malaria)
  • Toxoplasma gondii (toxoplasmosis)

Chemical Agents

Chemical agents and their CAS numbers, sources and toxological designations
Chemical Name CAS No Source Toxicological Designation
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea 13010-47-4 Prop 65 D
1,2-Dibromo-3-Chloropropane (DBCP) 96-12-8 Prop 65 M
1,3,5-Triglycidyl-s-triazinetrione 2451-62-9 LANL, ACGIH R
1,3-Dioxolane 646-06-0 ACGIH R
1,4-Butanediol Dimethanesulfonate (Busulfan) 55-98-1 Prop 65 D
1-3-Butadiene 106-99-0 Prop 65 D, F, M
1-Bromopropane 106-94-5 Prop 65 D, F, M
1-Chloro-2-propanol 127-00-4 ACGIH R
1-Hexene 592-41-6 ACGIH R
1-Nitropropane 108-03-2 Reprotext A+ N/A
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 1746-01-6 Prop 65 D
2,3-Xylidine 87-59-2 Reprotext A+ N/A
2,4-D Butyric acid 94-82-6 Prop 65 M
2,4-Xylidine 95-68-1 Reprotext A+ N/A
2,5-Xylidine 95-78-3 Reprotext A+ N/A
2,6-Xylidine 87-62-7 Reprotext A+ N/A
2-Bromopropane 75-26-3 Prop 65 F, M
2-Chloro-1-propanol 78-89-7 ACGIH R
2-Chloropropionic Acid 598-78-7 LANL, ACGIH R
2-Ethoxyethanol (EGEE) 110-80-5 LANL, ACGIH R
2-Ethoxyethyl Acetate (EGEEA) 111-15-9 LANL, ACGIH R
2-Ethylhexanoic Acid 149-57-5 ACGIH N/A
2-Methoxyethanol (EGME) 109-86-4 LANL, ACGIH R
2-Methoxyethyl Acetate (EGMEA) 110-49-6 LANL, ACGIH R
2-Nitropropane 79-46-9 Reprotext A+ N/A
3,4-Xylidine 95-64-7 Reprotext A+ N/A
3,5-Xylidine 108-69-0 Reprotext A+ N/A
4,6-Dinitro-o-cresol 534-52-1 Reprotext A+ N/A
4,6-Dinitro-o-cresol Diethylamine Salt N/A Reprotext A+ N/A
4,6-Dinitro-o-cresol Sodium Salt 2312-76-7 Reprotext A+ N/A
Acetazolamide 59-66-5 Prop 65 D
Acetohydroxamic acid 546-88-3 Prop 65 D
Acrylic acid 79-10-7 LANL, ACGIH R
Actinomycin D 50-76-0 Prop 65 D
All-trans Retinoic Acid 302-79-4 Prop 65 D
Alprazolam 28981-97-7 Prop 65 D
Altretamine 645-05-6 Prop 65 D, M
Amantadine Hydrochloride 665-66-7 Prop 65 D
Amikacin Sulfate 39831-55-5 Prop 65 D
Aminoglutethimide 125-84-8 Prop 65 D
Aminoglycosides N/A Prop 65 D
Aminomesitylene 88-05-1 Reprotext A+ N/A
Aminopterin 54-62-6 Prop 65 D, F
Amiodarone Hydrochloride 19774-82-4 Prop 65 D, F, M
Amitraz 33089-61-1 Prop 65 D
Amitrole 61-82-5 LANL, ACGIH R
Ammonium Nitrate 6484-52-2 Reprotext A+ N/A
Amoxapine 14028-44-5 Prop 65 D
Amyl Nitrate 1002-16-0 Reprotext A+ N/A
Anabolic Steroids N/A Prop 65 F, M
Angiotensin Converting Enzyme (ACE) Inhibitors N/A Prop 65 D
Aniline 62-53-3 Reprotext A+ N/A
Anisindione 117-37-3 Prop 65 D
Arsenic (inorganic oxides) 7740-38-2 Prop 65 D
Aspirin 50-78-2 Prop 65 D, F
Atenolol 29122-68-7 Prop 65 D
Auranofin 34031-32-8 Prop 65 D
Azathioprine 446-86-6 Prop 65 D
Barbiturates N/A Prop 65 D
B-Chloroprene 126-99-8 ACGIH R
Beclomethasone Dipropionate 5534-09-8 Prop 65 D
Benomyl 17804-35-2 ACGIH D, M
Benzene 71-43-2 Prop 65 D, M
Benzodiazepines N/A Prop 65 D
Benzphetamine Hydrochloride 5411-22-3 Prop 65 D
Bischloroethyl Nitrosourea (BCNU) (Carmustine) 154-93-8 Prop 65 D
Bromacil Lithium Salt 53404-19-6 Prop 65 D, M
Bromoadiolone 28772-56-7 Reprotext A+ N/A
Bromoxynil 1689-84-5 Prop 65 D
Bromoxynil Octanoate 1689-99-2 Prop 65 D
Butabarbital Sodium 143-81-7 Prop 65 D
Butyl benzyl Phthalate (BBP) 85-68-7 Prop 65 D
Butyric Acid 305-03-3 Reprotext A+ D
Cadmium 7440-43-9 Prop 65 D, M
Carbamazepine 298-46-4 Prop 65 D
Carbaryl (Sevin) 63-25-2 LANL, ACGIH R
Carbon Disulfide 75-15-0 Reprotext A+ D, F, M
Carbon Monoxide 630-08-0 ACGIH, A+ D
Carboplatin 41575-94-4 Prop 65 D
Chenodiol 474-25-9 Prop 65 D
Chlorambucil 305-03-3 Prop 65 D
Chlorcyclizine Hydrochloride 1620-21-9 Prop 65 D
Chlordecone (Kepone) 143-50-0 Prop 65 D
Chlordiazepoxide 58-25-3 Prop 65 D
Chlordiazepoxide Hydrochloride 438-41-5 Prop 65 D
Chloroform 67-66-3 LANL, ACGIH R
Chlorophacinone 3691-35-8 Reprotext A+ N/A
Chlorsulfuron 64902-72-3 Prop 65 D, F, M
Cidofovir 113852-37-2 Prop 65 D, F, M
Cladribine 4291-63-8 Prop 65 D
Clarithromycin 81103-11-9 Prop 65 D
Clobetasol Propionate 25122-46-7 Prop 65 D, F
Clomiphene Citrate 50-41-9 Prop 65 D
Clorazepate Dipotassium 57109-90-7 Prop 65 D
Cobalt (II) Nitrate 10141-05-6 Reprotext A+ N/A
Cocaine 50-36-2 Prop 65 D, F
Codeine Phosphate 52-28-8 Prop 65 D
Colchicine 64-86-8 Prop 65 D, M
Conjugated Estrogens N/A Prop 65 D
Copper Sulfate 7758-98-7 Reprotext A+ N/A
Coumarin 5836-29-3 Reprotext A+ N/A
Cupric Nitrate 3251-23-8 Reprotext A+ N/A
Cyanazine 21725-46-2 Prop 65 D
Cycloate 1134-23-2 Prop 65 D
Cycloheximide 66-81-9 Prop 65 D
Cyclophosphamide (anhydrous) 50-18-0 Prop 65 D,F, M
Cyclophosphamide Hydrate 6055-19-2 Prop 65 D,F, M
Cyhexatin 13121-70-5 Prop 65 D
Cytarabine 147-94-4 Prop 65 D
Dacarbazine 4342-03-4 Prop 65 D
Danazol 17230-88-5 Prop 65 D
Daunorubicin Hydrochloride 23541-50-6 Prop 65 D
DDT 50-29-3 Prop 65 D, F, M
Demeclocycline Hydrochloride 64-73-3 Prop 65 D
Di(2-ethylhexyl)phthalate (DEHP) 117-81-7 Prop 65 D, M
Diazepam 439-14-5 Prop 65 D
Diazoxide 364-98-7 Prop 65 D
Dichlorophene 97-23-4 Prop 65 D
Dichlorphenamide 120-97-8 Prop 65 D
Diclofop Methyl 51338-27-3 Prop 65 D
Dicumarol 66-76-2 Prop 65 D
Diethylstilbestrol 56-53-1 Reprotext A+ D
Diflunisal 22494-42-4 Prop 65 D, F
Diglycidyl ether (DGE) 2238-07-5 LANL, ACGIH, B- R
Dihydroergotamine Mesylate 6190-39-2 Prop 65 D
Di-isodecyl Phthalate (DIDP) 26761-40-0 Prop 65 D
Diltiazem Hydrochloride 33286-22-5 Prop 65 D
Di-n-butyl Phthalate 84-74-2 Prop 65 D, F, M
Di-n-hexyl Phthalate 84-75-3 Prop 65 F, M
Dinitrotoluene 25321-14-6 ACGIH, A+ F, M
Dinoseb 88-85-7 Prop 65 D, M
Diphacinone 82-66-6 Reprotext A+ N/A
Doxorubicin Hydrochloride 25316-40-9 Prop 65 D, M
Epichlorohydrin 106-89-8 Prop 65 M
Ethyl Acetate 141-78-6 Reprotext A+ N/A
Ethyl tert-butyl ether (ETBE) 637-92-3 LANL, ACGIH R
Ethylene Dibromide (EDB) 106-93-4 LANL D, M
Ethylene Glycol Monethyl Ether Acetate 111-15-9 Prop 65 D, M
Ethylene Glycol Monoethyl Ether 110-80-5 Prop 65 D, M
Ethylene Glycol Monomethyl Ether 109-86-4 Prop 65 D, M
Ethylene Glycol Monomethyl Ether Acetate 110-49-6 Prop 65 D, M
Ethylene Oxide 75-21-8 ACGIH F
Ethylenediamine 107-15-3 Reprotext A+ N/A
Etodolac 41340-25-4 Prop 65 D, F
Ferric Nitrate 10421-48-4 Reprotext A+ N/A
Flunisolide 3385-03-3 Prop 65 D, F
Fluorouracil 51-21-8 Reprotext A+ D
Fluoxetine 54910-89-3 Reprotext A+ N/A
Fluoxetine Hydrochloride 59333-67-4 Reprotext A+ N/A
Flurbiprofen 5104-49-4 Prop 65 D, F
Ganciclovir Sodium 82410-32-0 Prop 65 D, M
Gemfibrozil 25812-30-0 Prop 65 F, M
Goserelin Acetate 65807-02-5 Prop 65 D, F, M
Haloperidol 52-86-8 Prop 65 D, F
Halothane 151-67-7 LANL, ACGIH D
Hexafluoroacetone 684-16-2 LANL, ACGIH R
Hydramethylnon 67485-29-4 Prop 65 D, M
Idarubicin Hydrochloride 57852-57-0 Prop 65 D, M
Iodine 7553-56-2 Reprotext A+ N/A
Iodine-131 N/A 10043-66-0 D
Lead 7439-92-1 Reprotext 'A+, ACGIH D, F, M
Lead Arsenate as Pb3(AsO4)2 3687-31-8 ACGIH R
Lead Chromate 7758-97-6 ACGIH R
Lead Diamyldithiocarbamate N/A Reprotext A N/A
Lead Dioxide 1309-60-0 Reprotext A+ N/A
Lead Naphthenate 61790-14-5 Reprotext A N/A
Lead Nitrate 10099-74-8 Reprotext A+ N/A
Lead Oxide 1317-36-8 Reprotext A+ N/A
Lead Tetroxide 1314-41-6 Reprotext A+ N/A
Leuprorelin Acetate 74381-53-6 Prop 65 D, F, M
Levodopa 59-92-7 Prop 65 D
Levonorgestrel Implants 797-63-7 Prop 65 F
Linuron 330-55-2 Prop 65 D
Lithium Carbonate 554-13-2 Prop 65 D
Lithium Citrate 919-16-4 Prop 65 D
Lorazepam 846-49-1 Prop 65 D
Lovastatin 75330-75-5 Prop 65 D
Magnesium Nitrate 10377-60-3 Reprotext A+ N/A
Magnesium Silicofluoride 18972-56-0 Reprotext A N/A
Manganese 7439-96-5 LANL, ACGIH R
m-Dinitrobenzene 99-65-0 Prop 65 M
Mebendazole 31431-39-7 Prop 65 D
Medroxyprogesterone Acetate 71-58-9 Prop 65 D
Megestrol Acetate 595-33-5 Prop 65 D
Melphalan 148-82-3 Prop 65 D
Menotropins 9002-68-0 Prop 65 D
Meprobamate 57-53-4 Prop 65 D
Mercaptopurine 6112-76-1 Prop 65 D
Mercuric Chloride 7487-94-7 Reprotext A+ N/A
Mercuric Iodide 7774-29-0 Reprotext A+ N/A
Mercury 7439-97-6 LANL, ACGIH D, R
Methacycline Hydrochloride 3963-95-9 Prop 65 D
Metham Sodium 137-42-8 Prop 65 D
Methazole 20354-26-1 Prop 65 D
Methimazole 60-56-0 Prop 65 D
Methotrexate 59-05-2 Reprotext A+ N/A
Methotrexate 59-05-2 Prop 65 D
Methotrexate Sodium 15475-56-6 Prop 65 D
Methoxyethyl Mercuric Acetate 151-38-2 Reprotext A+ N/A
Methyl Bromide 15475-56-6 Prop 65 D
Methyl Chloride 74-87-3 LANL, ACGIH D, R
Methyl Isocyanate 624-83-9 Reprotext A+ N/A
Methyl Mercury N/A Prop 65 D
Methyl Tert-Butyl Ether (MTBE) 1634-04-4 LANL, ACGIH R
Methylene Chloride 75-09-2 Reprotext A+ N/A
Methylmercuric Dicyanamide 502-39-6 Reprotext A+ N/A
Methyltestosterone 58-18-4 Prop 65 D
Metiram 9006-42-2 Prop 65 D
Midazolam Hydrochloride 59467-96-8 Prop 65 D
Minocycline Hydrochloride (internal use) 13614-98-7 Prop 65 D
Misoprostol 59122-46-2 Prop 65 D
Mitoxantrone Hydrochloride 70476-82-3 Prop 65 D
Molybdated Lead Chromate 12213-61-5 Reprotext A N/A
Molybdated Lead Chromate 12656-85-8 Reprotext A N/A
Myclobutanil 88671-89-0 Prop 65 D, M
N,N-Dimethylacetamide 127-19-5 LANL, ACGIH R
Nabam 142-59-6 Prop 65 D
Nafarelin Acetate 86220-42-0 Prop 65 D
Naphthalene 91-20-3 Reprotext A+ N/A
n-Butyl Acrylate 141-32-2 LANL, ACGIH N/A
n-Butyl Mercaptan 109-79-5 LANL, ACGIH R
Nickel Carbonyl 13463-39-3 Reprotext A+ D
Nicotine 54-11-5 Prop 65 D
Nifedipine 21829-25-4 Prop 65 D, F, M
Nimodipine 66085-59-4 Prop 65 D
Nitrapyrin 1929-82-4 Prop 65 D
Nitrobenzene 98-95-3 Reprotext A+ N/A
Nitrofurantoin 67-20-9 Reprotext A+ M
Nitrogen Mustard (Mechlorethamine) 51-75-2 Prop 65 D
Nitrogen Mustard Hydrochloride 55-86-7 Prop 65 D
Nitrous Oxide 10024-97-2 LANL, ACGIH R
N-Methylpyrrolidone 872-50-4 Prop 65 D
Norethisterone (Norethindrone) 68-22-4 Prop 65 D
Norethisterone acetate (Norethindrone acetate) 51-98-9 Prop 65 D
Norgestrel 6533-00-2 Prop 65 D
o-Dinitrobenzene 528-29-0 Prop 65 M
Oxadiazon 19666-30-9 Prop 65 D
Oxazepam 604-75-1 Prop 65 D
Oxydemeton Methyl 301-12-2 Prop 65 F, M
Oxymetholone 434-07-1 Prop 65 D
Oxytetracycline (internal use) 79-57-2 Prop 65 D
Oxytetracycline hydrochloride (internal use) 2058-46-0 Prop 65 D
Oxythioquinox (Chinomethionat) 2439-01-2 Prop 65 D
Paclitaxel 33069-62-4 Prop 65 D, F, M
Paramethadione 115-67-3 Prop 65 D
PCB 1336-36-3 Reprotext A+ N/A
PCB (Aroclor 1016) 12674-11-2 Reprotext A+ N/A
PCB (Aroclor 1221) 11104-28-2 Reprotext A+ N/A
PCB (Aroclor 1232) 11141-16-5 Reprotext A+ N/A
PCB (Aroclor 1242) 53469-21-9 Reprotext A+ N/A
PCB (Aroclor 1248) 12672-29-6 Reprotext A+ N/A
PCB (Aroclor 1254) 11097-69-1 Reprotext A+ N/A
PCB (Aroclor 1260) 11096-82-5 Reprotext A+ N/A
PCB (Aroclor 1262) 37324-23-5 Reprotext A+ N/A
PCB (Aroclor 1268) 11100-14-4 Reprotext A+ N/A
PCB (Kanechlor 400) 12737-87-0 Reprotext A+ N/A
p-Dinitrobenzene 100-25-4 Prop 65 M
Penicillamine 52-67-5 Prop 65 D
Pentobarbital sodium 57-33-0 Prop 65 D
Pentostatin 53910-25-1 Prop 65 D
Phenacemide 63-98-9 Prop 65 D
Phenol 108-95-2 Reprotext A+ N/A
Phenprocoumon 435-97-2 Prop 65 D
Phenytoin Sodium 630-93-3 Reprotext A+ N/A
Pimozide 2062-78-4 Prop 65 D, F
Pipobroman 54-91-1 Prop 65 D
Plicamycin 18378-89-7 Prop 65 D
Potassium Dimethyldithiocarbamate 128-03-0 Prop 65 D
Potassium Fluoride 7789-23-3 Reprotext A N/A
Potassium Permanganate 7722-64-7 Reprotext A+ N/A
Pravastatin Sodium 81131-70-6 Prop 65 D
Prednisolone Sodium Phosphate 125-02-0 Prop 65 D
Procarbazine Hydrochloride 366-70-1 Prop 65 D
Propargite 2312-35-8 Prop 65 D
Propylthiouracil 51-52-5 Reprotext A+ D
Pyrimethamine 58-14-0 Prop 65 D
Quazepam 36735-22-5 Prop 65 D
Quizalofop-ethyl 76578-14-8 Prop 65 M
Resmethrin 10453-86-8 Prop 65 D
Ribavirin 36791-04-5 Prop 65 D, M
Rifampin 13292-46-1 Prop 65 D, F
Secobarbital Sodium 309-43-3 Prop 65 D
Sermorelin Acetate N/A Prop 65 D
Sodium Dimethyldithiocarbamate 128-04-1 Prop 65 D
Sodium Fluoroacetate 62-74-8 Prop 65 M
Sodium Iodide 7681-82-5 Reprotext A+ N/A
Sodium Nitrite 7632-00-0 Reprotext A+ N/A
Sodium Silicofluoride 16893-85-9 Reprotext A N/A
Streptomycin Sulfate 3810-74-0 Prop 65 D
Streptozocin 18883-66-4 Prop 65 D, F, M
Strontium Nitrate 10042-76-9 Reprotext A+ N/A
Sulindac 38194-50-2 Prop 65 D, F
Tamoxifen Citrate 54965-24-1 Prop 65 D
Temazepam 846-50-4 Prop 65 D
Teniposide 29767-20-2 Prop 65 D
Terbacil 5902-51-2 Prop 65 D
tert -Amyl Methyl Ether (TAME) 994-05-8 ACGIH R
Testosterone Cypionate 58-20-8 Prop 65 D
Testosterone Enanthate 315-37-7 Prop 65 D
Tetracycline (internal use) 60-54-8 Prop 65 D
Tetracycline Hydrochloride (internal use) 64-75-5 Prop 65 D
Tetranitromethane 509-14-8 Reprotext A+ N/A
Thalidomide 50-35-1 Reprotext A+ D
Thioguanine 154-42-7 Prop 65 D
Thiophanate Methyl 23564-05-8 Prop 65 F, M
Tobacco Smoke (primary) N/A Prop 65 D, F, M
Tobramycin Sulfate 49842-07-1 Prop 65 D
Toluene 108-88-3 Reprotext A+ D
Triadimefon 43121-43-3 Prop 65 D, F, M
Triazolam 28911-01-5 Prop 65 D
Tributyltin Methacrylate 2155-70-6 Prop 65 D
Trientine Hydrochloride 38260-01-4 Prop 65 D
Triforine 26644-46-2 Prop 65 D
Trilostane 13647-35-3 Prop 65 D
Trimethadione 127-48-0 Prop 65 D
Trimetrexate Glucuronate 82952-64-5 Prop 65 D
Triphenyltin Hydroxide 76-87-9 Prop 65 D
Uracil Mustard 66-75-1 Prop 65 D, F, M
Uranium (VI) Dinitrate Oxide 13520-83-7 Reprotext A N/A
Urethane (Ethyl Carbamate) 51-79-6 Prop 65 D
Urofollitropin 97048-13-0 Prop 65 D
Valproate (Valproic acid) 99-66-1 Prop 65 D
Valproic Acid 99-66-1 Reprotext A+ N/A
Vinblastine Sulfate 143-67-9 Prop 65 D
Vinclozolin 50471-44-8 Prop 65 D
Vincristine Sulfate 2068-78-2 Prop 65 D
Vinyl Cyclohexene 100-40-3 LANL, ACGIH R
Vinyl Cylohexene Dioxide 106-87-6 LANL, ACGIH R
Warfarin 81-81-2 Reprotext A+ D
Warfarin Sodium 129-06-6 Reprotext A+ N/A
Xylidine 1300-73-8 Reprotext A+ N/A
Zileuton 111406-87-2 Prop 65 D, F

Physical Agents

High sound levels

Heavy work, including heavy lifting

Prolonged standing


  1. Livingston, E. G. (1998) Infectious Agents and Noninfectious Biologic Products, in Reproductive Hazards of the Workplace, Frazier, L. M., Hage, M. L. (eds.), John Wiley and Sons (New York), Chapter 20, pp. 463-505.
  2. Lawrence Berkeley National Laboratory Chemical Hygiene and Safety Plan, revised 02/14, Chapter 45, Appendix D, LBNL Reproductive Toxins spreadsheet,, accessed May 5, 2015.
  3. Greenberg, G. N., Cohen, B. A., Frazier, L. M., DeHart, R. L. (1998) Noise, Ultrasound, and Vibration, in Reproductive Hazards of the Workplace, Frazier, L. M., Hage, M. L. (eds.), John Wiley and Sons (New York), Chapter 17, pp. 401-414.
  4. Nesbitt, T. (1998) Ergonomic Exposures, in Reproductive Hazards of the Workplace, Frazier, L. M., Hage, M. L. (eds.), John Wiley and Sons (New York), Chapter 19, pp. 431-462.