Particularly Hazardous Substances

CARCINOGENS – OSHA, IARC Group 1 and NTP Type 1

2-Acetylaminofluorene

Acrylonitrile

Aflatoxins

4-Aminobiphenyl

Arsenic (and As compounds)

Asbestos

Azathioprine

Benzene

Benzidine

Beryllium (and Be compounds)

Bis(chloromethyl)ether

1,3-Butadiene

1,4-Butanediol dimethylsulfonate (myleran)

Cadmium (and Cd compounds)

Chlorambucil

N,N-bis(2-Chloroethyl)-2-naphthylamine

1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea

Chloromethylmethyl ether

Chromium (VI) compounds

Ciclosporin Coal tars (and volatiles and extracts)

Cyclophosphamide

1,2-Dibromo-3-chloroproprane

3,3’-Dichlorobenzidine (and its salts)

Diethylstilbestrol

4-Dimethylaminoazobenzene

N,N-Dimethylnitrosoamine

Erionite

Estrogens (conjugated)

Ethylene oxide

Ethylenimine

Formaldehyde

Melphalan

8-Methoxypsoralen plus UV radiation

Methylchloromethylether

4,4’-Methylenedianiline

Mineral Oils (untreated and mildly treated)

Mustard gas (bis(2-chloroethyl)sulfide)

α-Naphthylamine

β-Naphthylamine

Nickel (and Ni compounds)

4-Nitrobiphenyl

N-Nitrosodimethylamine

Oestrogens (steroidal and non-steroidal)

Oral contraceptives (combined and sequential)

Phenacetin contained in analgesic mixtures

β-Propiolactone

Radon

Shale Oils

Silica (crystalline)

Soots (containing PAHs)

Tamoxifen

2,3,7,8-Tetrachlorodibenzo-p-dioxin

Thiotepa

Thorium dioxide

Tobacco Smoke (and smokeless tobacco)

Treosulfan

Vinyl Chloride

Wood Dust (certain hard woods)

EXAMPLES OF REPRODUCTIVE TOXINS – not all inclusive

Arsenic (and certain As compounds)

Benzene

Cadmium (and certain Cd compounds)

Carbon disulfide

Ethylene glycol monomethyl and ethyl ethers

Ethylene oxide

Lead compounds

Mercury compounds

Vinyl Chloride

Xylene

EXAMPLES OF CHEMICALS WITH HIGH ACUTE TOXICITY – not all inclusive

Acrolein

Arsine

Chlorine

Diazomethane

Diborane (gas)

Hydrogen cyanide

Hydrogen fluoride

Methyl fluorosulfonate

Nickel carbonyl

Nitrogen dioxide

Osmium tetroxide

Ozone

Phosgene

Sodium azide

Sodium cyanide (and cyanide salts)