Particularly Hazardous Substances
CARCINOGENS – OSHA, IARC Group 1 and NTP Type 1
2-Acetylaminofluorene
Acrylonitrile
Aflatoxins
4-Aminobiphenyl
Arsenic (and As compounds)
Asbestos
Azathioprine
Benzene
Benzidine
Beryllium (and Be compounds)
Bis(chloromethyl)ether
1,3-Butadiene
1,4-Butanediol dimethylsulfonate (myleran)
Cadmium (and Cd compounds)
Chlorambucil
N,N-bis(2-Chloroethyl)-2-naphthylamine
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
Chloromethylmethyl ether
Chromium (VI) compounds
Ciclosporin Coal tars (and volatiles and extracts)
Cyclophosphamide
1,2-Dibromo-3-chloroproprane
3,3’-Dichlorobenzidine (and its salts)
Diethylstilbestrol
4-Dimethylaminoazobenzene
N,N-Dimethylnitrosoamine
Erionite
Estrogens (conjugated)
Ethylene oxide
Ethylenimine
Formaldehyde
Melphalan
8-Methoxypsoralen plus UV radiation
Methylchloromethylether
4,4’-Methylenedianiline
Mineral Oils (untreated and mildly treated)
Mustard gas (bis(2-chloroethyl)sulfide)
α-Naphthylamine
β-Naphthylamine
Nickel (and Ni compounds)
4-Nitrobiphenyl
N-Nitrosodimethylamine
Oestrogens (steroidal and non-steroidal)
Oral contraceptives (combined and sequential)
Phenacetin contained in analgesic mixtures
β-Propiolactone
Radon
Shale Oils
Silica (crystalline)
Soots (containing PAHs)
Tamoxifen
2,3,7,8-Tetrachlorodibenzo-p-dioxin
Thiotepa
Thorium dioxide
Tobacco Smoke (and smokeless tobacco)
Treosulfan
Vinyl Chloride
Wood Dust (certain hard woods)
EXAMPLES OF REPRODUCTIVE TOXINS – not all inclusive
Arsenic (and certain As compounds)
Benzene
Cadmium (and certain Cd compounds)
Carbon disulfide
Ethylene glycol monomethyl and ethyl ethers
Ethylene oxide
Lead compounds
Mercury compounds
Vinyl Chloride
Xylene
EXAMPLES OF CHEMICALS WITH HIGH ACUTE TOXICITY – not all inclusive
Acrolein
Arsine
Chlorine
Diazomethane
Diborane (gas)
Hydrogen cyanide
Hydrogen fluoride
Methyl fluorosulfonate
Nickel carbonyl
Nitrogen dioxide
Osmium tetroxide
Ozone
Phosgene
Sodium azide
Sodium cyanide (and cyanide salts)