George 'Jake' Wendt

Research Faculty
Wendt, George

Summary

Mr. Wendt has a broad programming and IT background with experience in multiple disciplines and full-stack development experience from system, database, web and software development and administration in a Linux environment. His previous work includes NASA projects like data processing of SOHO/LASCO at the Naval Research Laboratory, DC, INTEGRAL in Versoix, Switzerland and the NVO at Goddard Space Flight Center, MD. He is currently working on several biomedical, genomic and proteomic research projects focusing on cancer at the University of Nevada, the University of California, Berkeley and University of California, San Francisco.

During the past two decades, Mr. Wendt has developed complex automation bash scripts, pipelines and workflows, data parsing scripts with awk, scientific data processing, image reduction / movie production and full stack rails apps. He uses cloud resources from AWS, Azure and Google and cluster computing with slurm/scyld, AWS Batch and developed custom cloud cluster management software with a database-driven queue (dbQ).

His most exciting projects involve massive next-generation sequencing datasets where he has developed a number of bioinformatic pipelines that range in function, including calling novel retro-element insertions from whole genome data, categorizing the metagenome from RNA-seq, conducting tumor-normal subtraction and calling somatic mutational signatures.

He developed the Antimicrobial Resistance Intelligence System (ARIS) prototype on the University of Nevada, Reno's WolfCloud.

Most recently he was awarded $15,000 in AWS Cloud Credits for Research to investigate the viral content of the entire 1000 Genomes DNA data set, currently publicly available on S3, and the entire Genetic European Variation in Disease (GEUVADIS) RNA data set, whose subjects represent a small subset of 1000 Genomes. These combined analyses will provide us with the opportunity to determine active and dormant infection rates amongst the populations, as well as correlations to any other available metadata.

Mr. Wendt is also currently representing the school on the University's Cyber-Infrastructure Committee and is expected to take on the role as Research Technology Facilitator for the School of Community Health Sciences to interface between researchers and OIT and better ensure that researchers have access to all of the tech tools needed to be successful in their projects.

He is always available to assist other researchers.

Education

  • BA in Physics and Astronomy, North Carolina, Greensboro