Xiaoshan Zhu

Associate Professor

Phone: (775) 682-6298
Email: xzhu@unr.edu
Building: SEM
Room: 337A
Mailstop: 0260
Website: Dr. Zhu's website

B. Sreenan, B. Lee, L. Wan, R. Zeng, J. Zhao, Xiaoshan Zhu*, Review of Development of Mn Doped Nanocrystals for Time-Resolved Luminescence Biosensing/Imaging, ACS Applied Nano Materials, 2022. DOI: 10.1021/acsanm.2c04337.
Y. Chen, R. Zeng, Q. Wei, S. Zhang, Y. Wang, C. Chen, Xiaoshan Zhu, S. Cao, B. Zou, J. Zhang, Competing-Energy-Transfer Modulated Dual Emission in Mn2+-Doped Cs2NaTbCl6 Rare-Earth Double Perovskites, Journal of Physical Chemistry Letters, 2022, 13, 8529-8536. DOI: 10.1021/acs.jpclett.2c02491.
T. Chang, Q. Wei, Z. Wang, Y. Gao, B. Lian, Xiaoshan Zhu, S. Cao, J. Zhao, B. Zou, R. Zeng, Phase-Selective Solution Synthesis of Cd-Based Perovskite Derivatives and Their Structure/Emission Modulation, Journal of Physical Chemistry Letters, 2022, 13, 3682–3690, DOI: 10.1021/acs.jpclett.2c00863.
B. Lee, S. Tian, G. Xiong, Y. Yang, Xiaoshan Zhu*, Solvothermal Synthesis of Transition-metal (Fe/Cu) and Nitrogen Co-Doped Carbon Nanomaterials: Comparing Their Peroxidase-like Properties, Journal of Nanoparticle Research, 2022, 24:85, DOI:10.1007/s11051-022-05470-y.
B. Lee, T. Hegseth, Xiaoshan Zhu*, Optical Properties of Mn Doped CuGa(In)S-ZnS Nanocrystals (NCs): Effects of Host NC and Mn Concentration, Nanomaterials, 2022, 12, 6: 994, DOI:10.3390/nano12060994.
T. Hegseth, B. Lee, D. Aucoin, Xiaoshan Zhu*, A Compact and Sensitive Time-Resolved-Optical-Reader for Bioassay Using Low-Energy Excitable and Long-Lived-Fluorescence Nanolabels, IEEE Sensors Letters, 2022, 6, 4, 5000304, DOI:10.1109/LSENS.2022.3159761.
B. Lee, T. Hegseth, Y. Song, J. Zhao, Xiaoshan Zhu*, Mn-Doped AgZnInS/ZnS Nanocrystals (NCs): Effects of Zn Etching on the NC Optical Properties, Optical Materials, 2022, 123, 111941. DOI:10.1016/j.optmat.2021.111941.
V. G. Demillo, Xiaoshan Zhu*, Composites and Compositions for Therapeutic Use and Methods of Making and Using The Same, US Patent No. US 10,994,031, B2, May 4, 2021. (83 Pages)
B. Gallian, M. Saber Zaeimian, D. Hau, D. AuCoin, Xiaoshan Zhu*, A Highly Sensitive Time-Gated Fluorescence Immunoassay Platform Using Mn Doped AgZnInS/ZnS Nanocrystals as Signal Transducers, Frontiers in Physics: Optics and Photonics (Modern Tools for Time-Resolved Luminescence Biosensing and Imaging), 2021, 8:625424, DOI: 10.3389/fphy.2020.625424. (Invited)
M. Saber Zaeimian, D. AuCoin, Xiaoshan. Zhu*, Immunoassay Using Dendritic Au-Pt Nanoparticles as Signal Labels for Detection of the Biomarker of Burkholderia Pseudomallei, Journal of Nanoparticle Research, 2020, 22:323, DOI: 10.1007/s11051-020-05054-8.
C. Harrison, B. Gallian, G. Dong, Y. Wang, J. Zhao, Xiaoshan Zhu*, Mn Doped Cu-Zn-In-S/ZnS Nanocrystals: Optical Properties and Their Use as Time-Gated Fluorescence Probes, Journal of Nanoparticle Research, 2019, 21:248, DOI: 10.1007/s11051-019-4666-3.
B. Gallian, G. Dong, Xiaoshan Zhu*, A Compact Time-Gated Instrument for QDs with Low Excitation Energy and Millisecond Fluorescence Lifetime as Signal Reporters, and Its Detection Application, Review of Scientific Instruments, 2019, 90, 104701, DOI: 10.1063/1.5111147.
M. S. Zaeimian, B. Gallian, C. Harrison, Y. Wang, J. Zhao, Xiaoshan Zhu*, Mn Doped AZIS/ZnS Nanocrystals (NCs): Effects of Ag and Mn on NC Optical Properties, Journal of Alloys and Compounds, 2018, 765, 236-244.
S. Chen, M. S. Zaeimian, J. Monteiro, J. Zhao, A. G. Mamalis, A. de Bettencourt-Dias, Xiaoshan Zhu*, Mn Doped AIZS/ZnS Nanocrystals: Synthesis and Optical Properties, Journal of Alloys and Compounds, 2017, 725, 1077-1083.
Xiaoshan Zhu*, Low Cost, Efficient Dual Signal Amplification for Bioassays, US Patent No. US 9,482,616, B2, Nov 1, 2016. (53 Pages)
S. Chen, V. G. Demillo, M. Lu, Xiaoshan Zhu*, Preparation of Photoluminescence Tunable Cu-doped AgInS2 and AgInS2/ZnS Nanocrystals and Their Application as Cellular Imaging Probes, RSC Advances, 2016, 6, 51161-51170.
S. Chen, M. Ahmadiantehrani, J. Zhao, S. Zhu, A. G. Mamalis, Xiaoshan Zhu*, Heat-up Synthesis of Ag-In-S and Ag-In-S/ZnS Nanocrystals: Effect of Indium Precursors on Their Optical Properties, Journal of Alloys and Compounds, 2016, 665, 137–143.
V. G. Demillo, Xiaoshan Zhu*, Zwitterionic Amphiphile Coated Magnetofluorescent Nanoparticles – Synthesis, Characterization and Tumor Cell Targeting, Journal of Materials Chemistry B, 2015, 3, 8328-8336.
Z. Xiao, Xiaoshan Zhu, On-Chip Sensing of Thermoelectric Thin Film’s Merit, Sensors, 2015, 2015, 15, 17232-17240. (invited)
R. Shrake, V. G. Demillo, M. Ahmadiantehrani, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, Facilitated Preparation of Bioconjugatable Zwitterionic Quantum Dots Using Dual-Lipid Encapsulation, Journal of Colloid and Interface Science. 2015, 437, 140–146.
S. Chen, M. Ahmadiantehrani, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, Thermal Decomposition Based Synthesis of Ag-In-S/ZnS Quantum Dots and Their Chlorotoxin-Modified Micelles for Brain Tumor Cell Targeting, RSC Advances, 2015, 5, 60612-60620.
V.G. Demillo, M. Liao, D. Redelman, N. G. Publicover, K. W. Hunter Jr, Xiaoshan Zhu*, Fabrication of MnFe2O4-CuInS2/ZnS Magnetofluorescent Nanocomposites and Their Characterization, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2015, 464, 134–142.
L. Huang, M. Liao, S. Chen, V. G. Demillo, S. A. Dupre, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, A Polymer Encapsulation Approach to Prepare Zwitterion-like, Biocompatible Quantum Dots with Wide pH and Ionic Stability, Journal of Nanoparticle Research, 16, 2555-2564, 2014.
L. Huang, N. G. Publicover, K. W. Hunter Jr., M. Ahmadiantehrani, A. de Bettencourt-Dias, T. W. Bell, Xiaoshan Zhu*, Cadmium and Zinc Alloyed Cu-In-S Nanocrystals and Their Optical Properties, Journal of Nanoparticle Research, 15, 2056-2066, 2013.
C. Cowles, Xiaoshan Zhu*, MicroRNA Detection Using Magnetic Separation and Zinc-Based Nanolabels as Signal Transducers, Analytical Methods, 5, 801-804, 2013.
C. Cowles, Xiaoshan Zhu*, Dual Signal Amplification for Bioassays Using Ion Release of Nanolabels and Ion-Activated Enzyme Kinetics, Analyst, 137, 4815 – 4821, 2012.
C. Li, F. Pei, Xiaoshan Zhu, D. Duan, C. Zeng, Circulating MicroRNAs as Novel and Sensitive Biomarkers of Acute Myocardial Infarction, Clinical Biochemistry, 45, 727-732, 2012.
C. Cowles, B. Chen, Xiaoshan Zhu*, Facile Synthesis and Biosensing Application of Hybrid Zinc Nanoparticles, Journal of Nanoscience and Nanotechnology, 12, 4546–4552, 2012.
C. Cowles, Xiaoshan Zhu*, Sensitive Detection of Cardiac Biomarker Using ZnS Nanoparticles as Novel Signal Transducers, Biosensors and Bioelectronics, 30, 342-346, 2011.
C. Cowles, C. Pai, Xiaoshan Zhu*, Using Fluorescence Measurement of Zinc Ions Liberated from ZnS Nanoparticle Labels in Bioassay for Escherichia coli O157:H7, Journal of Nanoparticle Research, 13, 5407-5413, 2011.
C. Cowles, N. Publicover, Xiaoshan Zhu*, Fluorescence Signal Transduction Mechanism for Immunoassay Based on Zinc Ion Release from ZnS Nanocrystals, Analyst, 136, 2975 – 2980, 2011.
Xiaoshan Zhu*, Bead-Based Optical Immunoassay Using Quantum-Dot Labeling and Immunocomplex Dissociation for Detection of Escherichia coli O157:H7, Analytical Letters, 44, 874-884, 2011.
Xiaoshan Zhu*, D. Duan, S. Madsen, N. Publicover, Compatibility of Quantum Dots with Immunobuffers, and its Effect on Signal/Background of Quantum Dot-based Immunoassay, Analytical and Bioanalytical Chemistry, 369, 1345-1353, 2010.
Xiaoshan Zhu*, D. Duan, N. Publicover, Magnetic Bead Based Assay for C-Reactive Protein Using Quantum-Dot Fluorescence Labeling and Immunoaffinity Separation, Analyst, 135, 381-389, 2010.
Xiaoshan Zhu*, Micro/Nanoporous Membrane Based Gas-Water Separation in Microchannel, Microsystem Technologies, 15, 1459-1465, 2009.
A. Bange, J. Tu, Xiaoshan Zhu, C. Ahn, B. Halsall, W. Heineman, Electrochemical Detection of MS2 Phage Using a Bead-based Immunoassay and a NanoIDA, Electroanalysis, 19, 2202-2207, 2007.
Xiaoshan Zhu, and C. H. Ahn, On-chip Electrochemical Analysis System Using Nanoelectrodes and Bioelectronic CMOS Chip, IEEE Sensors Journal, 5, 1280- 1286, 2006. (cover page article)
Xiaoshan Zhu, and C. H. Ahn, Electrochemical Determination of Reversible Redox Species at Interdigitated Array Micro/Nanoelectrodes Using Charge Injection Method, IEEE Transaction on NanoBioscience, 4, 164-169, 2005.
Xiaoshan Zhu, C. Gao, J. W. Choi, P. L. Bishop and C. H. Ahn, On-Chip Generated Mercury Microelectrode for Heavy Metal Ion Detection, Lab Chip, 5, 212-217, 2005.
Xiaoshan Zhu, J. W. Choi, and C. H. Ahn, A New Dynamic Electrochemical Transduction Mechanism for Interdigitated Array Microelectrodes, Lab Chip, 4, 581 – 587, 2004.

Research interests

New chemical/physical properties of nanomaterials and their applications in bio-detection
Multi-modality bioimaging using engineered composite nanomaterials for disease diagnosis and therapy
Integrated sensor systems using bioMEMS technologies
Development, evaluation, and application of biosensors for environmental analysis, food safety, medicine, etc.

Xiaoshan Zhu

Education

Journal Articles and Patents (* presents the corresponding authorship or inventorship)