Minggen Lu, Ph.D.

Professor and Graduate Director of Health Analytics and Biostatistics
Minggen Lu

Summary

Lu's research areas include statistical methodology and its application in public health and biomedical sciences with focus on non-/semi-parametric regression, high-dimension data, large number theory, panel count data, survival data analysis, longitudinal data analysis, statistical computing, and statistical methods in epidemiology. In addition to active novel statistical methodology research, he has also engaged in collaborating with nationally and internationally recognized scholars in the areas of clinic medicine, nursing, opioid overdose, adolescent sexual behavior, nutrition and sports medicine.

Selected publications

Statistical methodology

An asterisk (*) denotes corresponding author.

  • Lu, M., Li, C. S., Wagner D. K. (2022+). Penalized estimation of partially linear additive zero-inflated Bernoulli regression model. Electronic Journal of Statistics. Under Review.
  • Lu, M. (2022+). Penalized estimation of panel count data using generalized estimating equation. Journal of Multivariate Analysis. Under Review.
  • Lu, M., Liu, Y., Li, C. S., Sun J. (2022+). An efficient penalized estimation approach for semi-parametric linear transformation models with interval-censored data. Statistics in Medicine. Accepted
  • Li, C. S., Lu, M. (2022+). Efficient estimation of a semiparametric zero-inflated Bernoulli regression model. Journal of Applied Statistics. In Press.
  • Liu, Y., Lu, M.*, McMahan, C. (2021). A penalized likelihood approach for efficiently estimating a partially linear additive transformation model with current status data. Electronic Journal of Statistics, 15(1), 2247-2287.
  • Lu, M., Li, C. S. (2020). Efficient estimation of semiparametric transformation models with current status data via penalized splines. Statistical Methods in Medical Research, 29(1), 3-14.
  • Lu, M., McMahan, C. (2018). A flexible, computationally efficient method for fitting a partially linear proportional hazards model to current status data. Biometrics, 74(4), 1240-1249.
  • Li, C. S., Lu, M. (2018). A lack-of-fit test for generalized linear models via single-index techniques. Computational Statistics, 33(2), 731-756.
  • Lu, M., Lu, T., Li, C. S. (2018). Efficient estimation of partially linear additive Cox model under monotonicity constraint. Journal of Statistical Planning and Inference, 192(1), 18-34.
  • Lu, M. (2018). Spline-based quasi-likelihood estimation of mixed Poisson regression with single-index models. Metrika, 81(1), 1-17.
  • Lu, M., Li, C. S. (2017). Penalized estimation for proportional hazards model with current status data. Statistics in Medicine, 36(30), 4893-4907.
  • Lu, M. (2017). Efficient estimation of quasi-likelihood models using B-splines. Annals of Institute of Statistical Mathematics, 36(5), 1099-1127.
  • Lu, M., Li, C.S. (2016). Spline-based semiparametric estimation of a zero-inflated Poisson regression single-index model. Annals of the Institute of Statistical Mathematics, 68(5), 1111-1134.
  • Lu, M. (2015). Spline estimation of generalized monotonic regression. Journal of Nonparametric Statistics, 27(1), 19-39.
  • Lu, M., Loomis, D. (2013). Spline-based semiparametric estimation of partially linear Poisson regression with single-index models. Journal of Nonparametric Statistics, 25(4), 905-922.
  • Lu, M., Yang, W. (2012) Multivariate logistic regression analysis of complex survey data with application to BRFSS data. Journal of Data Science, 10(2), 157-173.
  • Lu, M. (2010) Spline-based sieve maximum likelihood estimation in the partly linear model under monotonicity constraints. Journal of Multivariate Analysis, 101(10), 2528-2542.
  • Lu, M., Zhang, Y., Huang, J. (2009). Semiparametric estimation methods for panel count data using monotone B-splines. Journal of the American Statistical Association, 104(487), 1060-1070.
  • Lu, M., Zhang, Y., Huang, J. (2007). Estimation of the mean function with panel count data using monotone polynomial splines. Biometrika, 94(3), 705-718.

Health sciences

  • Johnson, L., Green Jr., H., Lu, M., Stockman, J., Felsher, M., Roth, A., Wagner, K. (2022+). Who Can I Ask? Who Would I Tell?: An Egocentric Network Analysis Among a Sample of Women At-Risk to Explore Anticipated Advice Seeking and Disclosure Around Pre-Exposure Prophylaxis (PrEP). AIDs and Behavior. Revise and Resubmit.
  • Tung, W.C., Jones, D., Lu, M. (2022+). Sources of Information and Communication about HPV among Chinese Students Attending U.S. Colleges: Implications for Culturally Appropriate Strategies. Journal of Transcultural Nursing. In Press.
  • Smith, K., Roy, O., Lu, M., Dawkins, A., Harding, R., Hepworth, K., Wagner, K. (2021). The mobile emergency recovery intervention trial (MERIT): Protocol for a 3-year mixed methods observational study of mobile recovery outreach teams in Nevada’s emergency departments. PLOS ONE, 16(10), e0258795.
  • Lensch, T., Clements-Nolle, K., Oman R. F., Evans W. P., Lu, M., Yang, W. (2021). Adverse childhood experiences (ACEs) and co-occurring psychological distress and substance abuse among juvenile offenders: The role of protective factors. Public Health, 194, 42-47.
  • Lensch, T., Clements-Nolle, K., Oman R. F., Evans W. P., Lu, M., Yang, W. (2021). Adverse childhood experiences and suicidal behaviors among youth: The buffering influence of family communication and school connectedness. Journal of Adolescent Health, 68(5), 945-952.
  • Lensch, T., Clements-Nolle, K., Oman, R., Lu, M. (2021). A longitudinal study of the protective influence of youth assets on juvenile arrest. Journal of Public Health, 43(2), 295-501.
  • D’Errico, M. P., Tung, W. C., Lu, M., D’Errico, R. (2021). Knowledge, Attitudes, and Practices Related to Human Papillomavirus Vaccination among College Students in a US State University: Implications for Nurse Practitioners. Journal of the American Association of Nurse Practitioners, 33(9), 709-718.
  • Tung, W. C., Lu, M., Langowski, J., Qiu, X. (2021). Reasons and Influential Recommendations Associated with HPV Vaccination among Chinese College Students in the USA. The Journal of American College Health, 69(6), 602-609.
  • Zhang, X., Oman, R. F., Larson, T. A., Christiansen, E. J., Granner, M. L., Lu, M., Yang, Y. (2020). Healthcare utilization, unmet service needs and HIV treatment outcomes among racial/ethnic groups. Health Behavior and Policy Review, 7(6), 584-595.
  • Zhang, X., Oman, R., Larson, T. A., Christiansen, E., Granner, M. L., Lu, M., Yang, Y. (2020). Healthcare utilization, unmet service needs and linkage to care among people living with HIV/AIDS. Journal of Public Health and Emergency, 4, 1-10.
  • Rahill, K., Oman, R. F., Fitch, A., Lu, M. (2020). Associations among environmental factors and physical activity behavior of airmen on a U.S. air force base. Health Behavior and Policy Review, 7(5), 473-480.
  • Wagner, K. D., Oman, R. F., Smith, K. P., Harding, R., Dawkins, A. D., Lu, M., Woodard, S., Berry, M. N., Roget, N. A. (2020). "Another tool for the tool box? I’ll take it!”: Feasibility and acceptability of mobile recovery outreach teams (MROT) for opioid overdose patients in the emergency room. Journal of Substance Abuse Treatment, 108, 95-103.
  • Zhang, X., Oman, R. F., Larson, T. A., Christiansen, E. J., Granner, M. L., Lu, M., Yang Y. (2020). Healthcare utilization, unmet service needs, and medication adherence among people living with HIV/AIDS. Current HIV Research, 18(6), 436-442.
  • Lensch, T., Clements-Nolle, K, Oman, R. F., Lu, M., Evans W. (2020). Prospective relationships between youth assets, negative life events, and binge drinking in a longitudinal cohort of youth. Annals of Epidemiology, 46, 24-30.
  • D'Errico, M., Tung, W. C., Lu, M. (2020). Barriers and Recommendations Associated with HPV Vaccination among College Students. The Journal for Nurse Practitioners, 16(7), 533-537.
  • Tung, W. C., Lu, M., Granner, M., McDonough, J., Ervin, S. (2019). Exploration of factors associated with perceived barriers to cervical cancer screening among Chinese American women. Journal of Public Health and Emergency, 3, 1-7.
  • Catapano, J., Chapman, A., Dull, M., Horner, L., Godzik, J., Brigeman, S., Morgan, C., Whiting, A., Lu, M., Zabramski, J., Fraser, D. (2019). Association of Angiotensin-Converting Enzyme Inhibitors with Increased Mortality among Patients with Isolated Severe Traumatic Brain Injury. Neurocritical Care, 31(3), 507-513.
  • Tung, W. C., Lu, M., Qiu X., Ervin S. (2019). Human Papillomavirus Knowledge, Attitudes, and Vaccination among Chinese College Students in the United States. Vaccine, 37(24), 3199-3204.
  • Clements-Nolle, K.D., Oman, R., Lu, M., Lensch, T., Moser, L. (2019). Youth assets and alcohol-related problems among male and female youth: Results from a longitudinal cohort study. Preventive Medicine, 123, 192-196.
  • Smith-Gagen, J., Larissa, L. W., Sanchez A., Shaun M. H., Tung, W. C., Lu, M. (2019). Nurse practitioner autonomy laws and their role in increasing timely Pap-smears among the underserved. Journal of Epidemiology & Community Health, 73(3), 278-284.
  • Tung, W. C., Granner, M., Lu, M., Sohn, J. (2019). Demographics, self-efficacy, benefits/barriers, stages of adopting Pap testing among Korean American women. Journal of Obstetrics and Gynaecology, 39(4), 510-515.
  • Lensch, T., Clements-Nolle, K. D., Oman, R., Lu, M. (2019). Prospective impact of individual, family, and community youth assets on adolescent suicide ideation. Journal of Epidemiology & Community Health, 73(3), 219-224.
  • Oman, R., Lensch, T., Amroussia, N., Clements-Nolle, K. D., Lu, M. (2019). The revised youth asset survey (YAS-R). American Journal of Health Promotion, 33(5), 768-773.
  • Oman, R., Clements-Nolle, K. D., Lu, M., Dominguez, A., Lensch, T. (2018). An Investigation of Youth Assets and Physical Activity and BMI Using a Longitudinal Cohort Design. American Journal of Health Promotion, 32(8), 1751-1754.
  • Catapano, J., Chapman, A., Farber, H., Horner, L., Morgan, C., Brigeman, S., Hendricks, B., Lu, M., Fraser, D. (2018). Treadmill associated head injuries on the rise: an 18 year review of U.S emergency room visits. Brian Injury, 32(6), 800-803.
  • Oman, R., Vesely, S., Green, J., Clements-Nolle, K. D., Lu, M. (2018). Effects of a teen pregnancy prevention intervention on youth living in group care homes: Results of a cluster randomized controlled trial. American Journal of Public Health, 108(S1), S38-S44.
  • Green, J., Oman, R. F., Lu, M., Fluhr, J. (2018). Impact of an intervention on teenage oral sex and dual contraceptive use. Health Behavior and Policy Review, 5(1), 47-56.
  • Tung, W. C., Lu, M., Granner, M., Sohn, J. (2017). Assessing perceived benefits/barriers and self-efficacy for cervical cancer screening among Korean American women. Health Care for Women International, 38(9), 1-11.
  • Green, J., Oman, R. F., Lu, M., Clements-Nolle, K. D. (2017). Long-term improvements in knowledge and psychosocial factors of a teen pregnancy prevention intervention implemented in group homes. Journal of Adolescent Health, 60(6), 698-705.
  • Tung, W. C., Granner, M., Lu, M., Qiu, X. (2017). Predictors of cervical cancer screening for Chinese American women. European Journal of Cancer Care, 26(4), e12552.
  • Tung, W. C., Lu, M., Granner, M. (2017). Perceived benefits and barriers of cervical cancer screening among Chinese American women. Oncology Nursing Forum, 44(2), 247-254.
  • Tung, W. C., Lu, M., Rull, R., Yang, W. (2017). Pilot test results of a video-based HIV intervention for Chinese college students in the United States. Journal of Public Health and Emergency, 1(83), 1-8.
  • Catapano, J. S., Chapman, A. J., Horner, L. P., Lu, M., Fraser, D. R., Fildes, J. J. (2017). Pre-injury polypharmacy predicts mortality in isolated severe traumatic brain injury patients. The American Journal of Surgery, 213(6), 1104-1108.
  • Mcphillamy, A., Moody, A., Gurnea, T., Kurnik, C., Lu, M. (2016). The Clinical and economic impact of generic locking plate utilization at a level II trauma center. Journal of Orthopaedic Trauma, 30(12), S32-S36.
  • Dai, H., Lu, S., Tang, X., Lu, M., Chen, R., Chen, Z., Yang, P., Liu, C., Zhou, H., Lu, Y., Yuan, H. (2016). Combined association of serum uric acid and metabolic syndrome with chronic kidney disease in hypertensive patients. Kidney Blood Pressure Research, 41(4), 413-423.
  • Lundeen, G., Clanton, T., Dunaway, L., Lu, M. (2016). Motion at the tibial and polyethylene component interface in a mobile bearing total ankle replacement. Foot & Ankle International, 37(8), 848-854.
  • Chen, S., Demillo, V., Lu, M., Zhu, X. (2016). Preparation of photoluminescence tunable cu-doped AgInS2 and AgInS2/ZnS nanocrystals and their application as cellular imaging probes. RSC Advance, 6(56), 51161-51170.
  • Tung, W. C., Lu, M., Smith-Gagen, J., Yao Y. (2016). Latina women and cervical cancer screening: decisional balance and self-efficacy. Clinical Journal of Oncology Nursing, 20(3), e71-e76.
  • Wen, J., Guo C. X., Lu, M., Lu, Y., Huang, Y., Liu, X., Li, Y., Huang, Z. J., Zhang, Y. P., Yuan, H. (2016). Gender-specific association between metabolic syndrome and decreased glomerular filtration rate in elderly population. International Urology and Nephrology, 48(3), 389-397.
  • Tung, W. C., Smith-Gagen, J., Lu, M., Warfield, M. (2016). Application of the Transtheoretical Model to cervical cancer screening in Latina women. Journal of Immigrant and Minority Health, 18(5), 1168-1174.
  • Hill, A. D., Catapano, J. S., Surina, J. B., Lu, M., Althausen, P. L. (2015). Clinical and economic impact of duplicated radiographic studies in trauma patients transferred to a regional trauma center. Journal of Orthopaedic Trauma, 29(7), e214-e218.
  • Zhang, Y. P., Lu, M., Duan, D. D., Liu, Y. L., Liu, M., Li, Y., Kuang, Z. M., Lu, Y., Liu, X., Li, X. H., Yuan, H. (2015). Association between high-density lipoprotein cholesterol and renal function in elderly hypertension: a cross-sectional study in Chinese population. Medicine, 94(14), e651.
  • Lu, Y., Lu, M., Dai, H., Yang, P., Smith-Gagen, J., Miao, R., Zhong, H., Chen, R., Liu, X., Huang, Z., Yuan, H. (2015). Lifestyle and risk of hypertension: follow-up of a young pre-hypertensive cohort. International Journal of Medical Sciences, 12(7), 605-612.
  • Tung, W. C., Serratt, T. D., Lu, M. (2015). Evidence-based HIV pilot program for Chinese college students: differences by gender. Nursing & Health Sciences, 17(2), 263-268.
  • Tung, W. C., Cook, D. M., Lu, M., Ding, K. (2015). A comparison of HIV knowledge, attitudes, and sources of STI information between female and male college students in Taiwan. Health Care for Women International, 36(8), 870-882.
  • Althausen, P. L., Kurnik, C. G., Shields, T., Anderson, S. R., Gurnea, T. P., Coll, D., Lu, M. (2014). Clinical and economic impact of using generic 7.3-mm cannulated screws at a level II trauma center. American Journal of Orthopedics, 43(9), 405-410.
  • Sigman-Grant, M., Byington, T. A., Lindsay, A. R., Lu, M., Mobley, A. R., Fitzgerald, N., Hildebrand, D. (2014). Preschoolers can distinguish between healthy and unhealthy foods: The All 4 Kids Study. Journal of Nutrition Education and Behavior, 46(2), 121-127.
  • Althausen, P. L., Kauk, J. R., Shannon, S., Lu, M., O’Mara, T. J., Bray, T. J. (2014). Operating room efficiency: benefits of an orthopaedic traumatologist at a level II trauma center. Journal of Orthopaedic Trauma, 28(5), e101-e106.
  • Althausen, P. L., Lu, M., Thomas, K. C., Shannon, S. F., Biagi, B. N., Boyden, E. M. (2014). Implant standardization for hemiarthroplasty: implementation of a pricing matrix system at a level II community based trauma system. The Journal of Arthroplasty, 29(4), 781-785.
  • Zhang, Y. P., Zuo, X. C., Huang, Z. J., Kuang, Z. M., Lu, M., Duan, D. D., Yuan, H. (2013). The impact of blood pressure on kidney function in the elderly: a cross-sectional study. Kidney and Blood Pressure Research, 38(2-3), 205-216.
  • Tung, W. C., Cook, D. M., Lu, M., Yang, W. (2013). HIV knowledge and health behavior among Chinese college students in the USA and China. Western Journal of Nursing Research, 35(9), 1171-1183.
  • Tung, W. C., Lu, M., Cook, D. M. (2013). HIV/AIDS knowledge and attitudes among Chinese college students in the US. Journal of Immigrant and Minority Health, 15(4), 788-795.
  • Althausen, P.L., Shannon, S., Owens, B., Coll, D., Cvitash, M., Lu, M., O'Mara, T. J., Bray, T.J. (2013). Impact of hospital-employed physician assistants on a level II community-based orthopaedic trauma system. Journal of Orthopaedic Trauma, 27(4), e87-e91.
  • Althausen, P. L., Shannon, S., Lu, M., O’Mara, T. J., Bray, T. J. (2013). Clinical and financial comparison of operative and nonoperative treatment of displaced clavicle fractures. Journal of Shoulder and Elbow Surgery, 22(5), 608-611.
  • Tung, W. C., Cook, D. M., Lu, M. (2012). Sexual behaviors, decisional balance, and self-efficacy among a sample of Chinese college students in the United States. Journal of American College Health, 60(5), 367-373.
  • Lindsay, A. R., Warren, C. S., Velasquez, S. C., Lu, M. (2012). A gender-specific approach to improving substance abuse treatment for women: the healthy steps to freedom program. Journal of Substance Abuse Treatment, 43(1), 61-69.
  • Yao, M., Lu, M., Savvides, P.S., Rezaee, R., Zender, C.A., Lavertu, P., Buatti, J.M., Machtay, M. (2012). Distant metastases in head-and-neck squamous cell carcinoma treated with intensity-modulated radiotherapy. International Journal of Radiation Oncology* Biology* Physics, 83(2), 684-689.
  • Tung, W. C., Cook, D. M., Lu, M. (2011). Sexual behavior, stages of condom use, and self-efficacy among college students in Taiwan. AIDS Care, 23(1), 113-120.
  • Shen, J. J., Lu, M. (2011). Changes in patterns of racial disparities in attending low-mortality hospitals and outcomes among patients with stroke. Ethnicity and Disease, 21(2), 135-141.
  • Sanchez, M. R., Tung, W. C., Amos, E. A., Lu, M. (2011). HPV prevention in high-risk males. The Journal for Nurse Practitioners, 7(1), 55-61.
  • Tung, W. C., Lu, M., Cook, D. M. (2010). Cervical cancer screening among Taiwanese women: a transtheoretical approach. Oncology Nursing Forum, 37(4), E288-94.
  • Tung, W. C., Lu, M., Cook, D. M. (2010). Papanicolaou screening in Taiwan: perceived barriers and self-efficacy. Health Care for Women International, 31(5), 421-434.
  • Tung, W. C., Lu, M., Cook, D. M. (2010). Condom use and stages of change among college students in Taiwan. Public Health Nursing, 27(6), 474-481.
  • Yao, M., Smith, R. B., Hoffman, H. T., Funk, G. F., Lu, M., Menda, Y., Graham, M. M.,Buatti, J. M. (2009). Clinical significance of postradiotherapy [18 F]-fluorodeoxyglucose positron emission tomography imaging in management of head-and-neck cancer long-term outcome report. International Journal of Radiation Oncology* Biology* Physics, 74(1), 9-14.

Education

  • Ph.D. in Biostatistics from the University of Iowa, Iowa City, IA
  • Ph.D. in Mathematics from Northeastern University, Boston, MA