Luis Schütz

Assistant Professor

Department: Agriculture, Veterinary and Rangeland Sciences
Office: 775-682-9408
Email: lschutz@unr.edu
Building: AE
Room: 202
Mailstop: 202

Summary

The ability of a cow to successfully mate, conceive, give birth to and raise a healthy calf each year is essential to Nevada’s beef and dairy industry. A good understanding of physiology of both the male and female is critical in successfully managing reproduction. Causes for failures in reproduction must be identified and overcome. Our research will lead to the development techniques for manipulating the reproductive processes. These techniques in beef production will provide new options to help modern beef and dairy producers accomplish their management goals.

Publications

Journals

Developmental and hormonal regulation of FBN1 and OR4M1 mRNA in bovine granulosa cells.

2023

Domest Anim Endocrinol. 2023 Jul-Oct;84-85:106791

Maylem ERS, Spicer LJ, Batalha IM, Schütz LF.

Effects of asprosin on estradiol and progesterone secretion and proliferation of bovine granulosa cells.

2023

Mol Cell Endocrinol. 2023 Apr 5;565:111890

Batalha IM, Maylem ERS, Spicer LJ, Pena Bello CA, Archilia EC, Schütz LF.

Effects of follicle-stimulating hormone, insulin-like growth factor 1, fibroblast growth factor 2, and fibroblast growth factor 9 on sirtuins expression and histone deacetylase activity in bovine granulosa cells.

2023

Theriogenology. 2023 Oct 15;210:1-8

Archilia EC, Bello CAP, Batalha IM, Wulstein K, Enriquez C, Schütz LF.

In vitro and in vivo embryo production efficiency in Flemish and Holstein donor females.

2023

Anim Reprod. 2023 Oct 30;20(3):e20230080

Zago FC, Schütz LF, Gerger RPDC, de Aguiar LH, Pinzón-Osorio CA, Mezzallira A, Rodrigues JL, Forell F, Bertolini M.

Changes in fibroblast growth factor receptors-1c, -2c, -3c, and -4 mRNA in granulosa and theca cells during ovarian follicular growth in dairy cattle

2022

Domestic Animal Endocrinology 80(6):106712

Schutz, Luis & Hemple, A.M. & Morrell, B.C. & Schreiber, N.B. & Gilliam, J.N. & Cortinovis, Cristina & Totty, Morgan & Caloni, Francesca & Aad, Pauline & Spicer, Leon.

Sperm DNA 5-methyl cytosine and RNA N6-methyladenosine methylation are differently affected during periods of body weight losses and body weight gain of young and mature breeding bulls

2022

Journal of Animal Science, Volume 100, Issue 2, February 2022, skab362

F.H Moura, A. Macias-Franco, C.A Pena-Bello, E.C Archilia, I.M Batalha, A.E M Silva, G.M Moreira, A.B Norris, L.F Schütz, M.A Fonseca

Effects of bone morphogenetic protein 4, gremlin, and connective tissue growth factor on estradiol and progesterone production by bovine granulosa cells.

2021

Journal of Animal Science, 99(11).

Spicer, L. J., Schutz, L. F., & Aad, P. Y.

Developmental and hormonal regulation of gene expression of fibrillin-1 (FBN1) and the asprosin receptor, olfactory receptor family 4 subfamily M member 1 (OR4M1), in bovine ovarian cells

2020

Journal of Animal Science, Volume 98, Issue Supplement 4

ER Maylem, L Spicer, I Batalha, L Schutz

Discovery of a possible role of asprosin in ovarian follicular function

2020

J. of Molecular Endocrinology, Volume 66: Issue 1

Maylem ERS, Spicer, L. J., Batalha, I., Schutz, L. f.

Hormonal regulation of vascular endothelial growth factor A (VEGFA) gene expression in granulosa and theca cells of cattle1.

2019

Journal of animal science, 97(7), 3034-3045

Nichols, J. A., Perego, M. C., Schutz, L. f., Hemple, A. M., Spicer, L. J.

Regulation of the transcription factor E2F1 mRNA in ovarian granulosa cells of cattle.

2019

Journal of animal science

Morrell, B. C., Perego, M. C., Maylem, E. R., Zhang, L., Schutz, L. f., Spicer, L. J.

Regulation of the transcription factor E2F8 gene expression in bovine ovarian cells.

2019

Molecular and cellular endocrinology, 498, 110572

Morrell, B. C., Zhang, L., Schutz, L. f., Perego, M. C., Maylem ERS, Spicer, L. J.

Effects of N-carbamylglutamate and L-arginine on steroidogenesis and gene expression in bovine granulosa cells.

2018

Anim Reprod Sci. 188:85-92

Feng T, Schütz LF, Morrell BC, Perego MC, Spicer LJ.

MicroRNA 221 expression in theca and granulosa cells: hormonal regulation and function.

2018

J Anim Sci. 96:641-652

Robinson CL, Zhang L, Schütz LF, Totty ML, Spicer LJ.

Transcriptome profiling of bovine ovarian theca cells treated with fibroblast growth factor 9.

2018

Domest Anim Endocrinol 63:48-58

Schütz LF, Hurst RE, Schreiber NB, Spicer LJ.

Effect of melatonin on bovine theca cells in vitro.

2017

Reprod Fertil Dev

Feng T, Schutz LF, Morrell BC, Perego MC, Spicer LJ.

Evidence for direct effects of glyphosate on ovarian function: glyphosate influences steroidogenesis and proliferation of bovine granulosa but not theca cells in vitro.

2017

J Appl Toxicol. 37:692-698

Perego MC, Schutz LF, Caloni F, Cortinovis C, Albonico M, Spicer LJ.

Evidence that gene expression of ovarian follicular tight junction proteins is regulated in vivo and in vitro in cattle.

2017

J Anim Sci 95:1313-1324

Zhang L, Schütz LF, Robinson CL, Totty ML, Spicer LJ.

G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications

2017

Domest Anim Endocrinol. 59:90-99

Spicer LJ, Schütz LF, Williams JA, Schreiber NB, Evans JR, Totty ML, Gilliam JN.

In vitro effects of the Fusarium mycotoxins fumonisin B1 and beauvericin on bovine granulosa cell proliferation and steroid production.

2017

Toxicon 128:38-45

Albonico M, Schutz LF, Caloni F, Cortinovis C, Spicer LJ.

Influence of a Roundup formulation on glyphosate effects on steroidogenesis and proliferation of bovine granulosa cells in vitro.

2017

Chemosphere 188:274-279

Perego MC, Caloni F, Cortinovis C, Schutz LF, Albonico M, Tsuzukibashi D, Spicer LJ.

Changes in brain ribonuclease (BRB) messenger RNA in granulosa cells (GCs) of dominant vs subordinate ovarian follicles of cattle and the regulation of BRB gene expression in bovine GCs

2016

Domest Anim Endocrinol 55:32-40

Dentis JL, Schreiber NB, Gilliam JN, Schutz LF, Spicer LJ.

Changes in fibroblast growth factor 9 mRNA in granulosa and theca cells during ovarian follicular growth in dairy cattle.

2016

J Dairy Sci. 99:9143-9151

Schütz LF, Schreiber NB, Gilliam JN, Cortinovis C, Totty ML, Caloni F, Evans JR, Spicer LJ.

Toxicological effects of fumonisin B1 alone and in combination with other fusariotoxins on bovine granulosa cells.

2016

Toxicon 118:47-53

Albonico M, Schütz LF, Caloni F, Cortinovis C, Spicer LJ.

Direct effects of the algal toxin, domoic acid, on ovarian function: Bovine granulosa and theca cells as an in vitro model

2015

Ecotoxicol Environ Saf 113:314-320

Pizzo F, Caloni F, Schreiber NB, Schutz LF, Totty ML, Albonico M, Spicer LJ.

Individual and combined effects of deoxynivalenol and a-zearalenol on cell proliferation and steroidogenesis of granulosa cells in cattle.

2015

Environ Toxicol Pharmacol 40:722-728

Pizzo F, Caloni F, Schutz LF, Totty ML, Spicer LJ.

Reviews

Current status of the role of endothelins in regulating ovarian follicular function: A review.

2017

Anim Reprod Sci. 186:1-10

Ervin JM, Schütz LF, Spicer LJ.