Andrew Nuss

Assistant Professor

Department: Agriculture, Veterinary and Rangeland Sciences
Office: 775-327-5096
Email: nussab@unr.edu
Building: FA
Room: 311b
Mailstop: 202

Summary

My research interests are focused on the physiology of neurohormonal signaling in insects of agricultural, medical, and veterinary importance. I am particularly interested in peptide hormones of the gut and their role in insect behavior, digestion, and nutrient storage. Projects include insecticide discovery by targeting peptide receptors and physiological functions of peptide hormones produced in the insect gut and nervous system.

Education

B.S., Entomology, Purdue University, 1998
M.S., Entomology, Purdue University, 2000
Ph.D., Entomology, University of Georgia, 2008

Publications

Book Chapter(s)

Chapter 9, Progress towards germline transformation of tick

2022

Transgenic Insects. Techniques and Applications

M. Pham, A.Sharma, A. Nuss, M. Gulia-Nuss

Journals

The highly improved genome of with X and Y pseudochromosomes

2023

Life science alliance 6

Andrew B Nuss, Johnathan S Lomas, Jeremiah B Reyes, Omar Garcia-Cruz, Wenlong Lei, Arvind Sharma, Michael N Pham, Saransh Beniwal, Mia L Swain, Molly McVicar, Isaac Amankona Hinne, Xingtan Zhang, Won C Yim, Monika Gulia-Nuss

Analyzing Blood Digestion: Estimation of Active Trypsin Levels in the Mosquito Midgut.

2022

Cold Spring Harb Protoc. 2023 Apr 3;2023(4):pdb.prot108224

Reyes, J. B., Nuss, A. B. & Gulia-Nuss, M.

Cas9-mediated gene editing in the black-legged tick, Ixodes scapularis, by embryo injection and ReMOT Control

2022

iScience Volume 25, Issue 3, 18 March 2022, 103781

A Sharma, M Pham, J Reyes, R Chana, WC Yim, CC Heu, D Kim, D Chaverra-Rodriguez, J Rasgon, R Harrell II, A Nuss, M Gulia-Nuss

Embryo Injection Technique for Gene Editing in the Black-Legged Tick, Ixodes scapularis

2022

J Vis Exp Sep 13;(187)

A. Sharma, M.Pham, R. Harrell II, A.Nuss, M. Gulia-Nuss

Genetic Manipulation of Ticks: A Paradigm Shift in Tick and Tick-Borne Diseases Research.

2021

Frontiers in Cellular and Infection Microbiology, 11, 678037

Nuss, A., Sharma, A., & Gulia-Nuss, M.

Blood Digestion by Trypsin-Like Serine Proteases in the Replete Lyme Disease Vector Tick, Ixodes scapularis

2020

Insects 2020, 11, 201; doi:10.3390/insects11030201

Jeremiah Reyes, Cuauhtemoc Ayala-Chavez, Arvind Sharma, Michael Pham, Andrew B Nuss, Monika Gulia-Nuss

The sugar substitute erythritol shortens the lifespan of Aedes aegypti potentially by N-linked protein glycosylation

2020

Scientific Reports

Arvind Sharma, Jeremiah Reyes, David Borgmeyer, Cuauhtemoc Ayala-Chavez, Katie Snow, Fiza Arshad, Andrew Nuss, Monika Gulia-Nuss

Dynamics of insulin signaling in the black-legged tick, Ixodes scapularis

2019

Front. Endocrinol.

Arvind Sharma, Rana Pooraiiouby, Blanca Guzman, Preston Vu, Monika Gulia-Nuss and Andrew Nuss

Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead.

2019

Front Endocrinol

Sharma A, Nuss AB, Gulia-Nuss M.

Chicago and Dovetail Hi-C proximity ligation yield chromosome length scaffolds of Ixodes scapularis genome

2018

BioRxiv

Andrew B Nuss, Arvind Sharma, Monika Gulia-Nuss.

Insulin receptor knockdown blocks filarial parasite development and alters egg production in the southern house mosquito, Culex quinquefasciatus.

2018

PLoS Neglected Tropical Diseases, 12(4)

Nuss, A., Brown, M., Murty, U., Gulia-Nuss, M.

Isolation of an insulin-like peptide from the Asian malaria mosquito, Anopheles stephensi, that acts as a steroidogenic gonadotropin across diverse mosquito taxa

2018

General and Comparative Endocrinology Volume 258, 1 March 2018, Pages 140-148

Nuss, A., Brown, M.

Nutritional stress affects Insulin-like peptides expression and physiology of the yellow fever mosquito Aedes aegypti.

2018

Insects, 9(3)

Pooraiiouby, R., Beard, J., Sharma, A., Reyes, J., Nuss, A., Gulia-Nuss, M.

Rearing Ixodes scapularis, the black-legged tick: feeding immature stages on mice.

2017

Journal of Visualized Experiments. 2017 May 8;(123)

Nuss, A., Mathew, M. G., M., Gulia-Nuss

Comparative pharmacological characterization of D1-like dopamine receptors from Anopheles gambiae, Aedes aegypti and Culex quinquefasciatus suggests pleiotropic signaling in mosquito vector lineages.

2016

Parasites and Vectors 9:192. doi:10.1186/s13071-016-1477-6

Hill CA, Doyle TB, Nuss AB, Ejendal KFK, Meyer JM, Watts VJ

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

2016

Nature Communications 7. doi:10.1038/ncomms10507

Gulia-Nuss M, Nuss AB, Meyer, JM, et al.

Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors.

2015

PLoS Neglected Tropical Diseases 9(3): e0003515. doi: 10.1371/journal.pntd.0003515

Nuss AB, Ejendal KFK, Doyle TB, Meyer JM, Lang EG, Watts VJ, Hill CA

Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti.

2015

Journal of Pharmacology and Experimental Therapeutics 352(1):53-60. doi: 10.1124/jpet.114.219717

Conley JM, Meyer JM, Nuss AB, Doyle TB, Savinov SN, Hill CA, Watts VJ

Human IGF1 extends lifespan and enhances resistance to Plasmodium falciparum infection in the malaria vector Anopheles stephensi.

2013

Journal of Experimental Biology 216(Pt 2):208-17. doi: 10.1242/jeb.078873

Drexler A, Nuss AB, Hauck E, Glennon E, Cheung K, Brown MR, Luckhart S

Insulin-like peptides in the mosquito Anopheles stephensi: Identification and expression in response to diet and infection with Plasmodium falciparum.

2011

General and Comparative Endocrinology 173:303-312.

Marquez AG, Pietri JE, Smithers HM, Nuss AB, Antonova Y, Drexler AL, Riehle MA, Brown MR, Luckhart S

Neuropeptide F and the corn earworm, Helicoverpa zea: a midgut peptide revisited.

2011

Peptides 32:483-492.

Huang Y, Crim JW, Nuss AB, Brown MR

Molecular Characterization of Neuropeptide F from the Eastern Subterranean Termite, Reticulitermes flavipes (Kollar) (Isoptera: Rhinotermitidae).

2010

Peptides 31:419-428.

Nuss AB, Forschler BT, Crim, JW, TeBrugge V, Pohl J, Brown MR

Distribution of Neuropeptide F-like Immunoreactivity in the Eastern Subterranean Termite, Reticulitermes flavipes (Isoptera: Rhinotermitidae).

2008

Journal of Insect Science 8:68.

Nuss AB, Forschler BT, Crim, JW, Brown MR

Continuous monitoring of the trail behavior of the black carpenter ant, Camponotus pennsylvanicus (Hymenoptera: Formicidae).

2005

Sociobiology 45: 597-618.

Nuss AB, Suiter DR, Bennett GW