Journals
Cardiac-specific deficiency of 3-hydroxy-3-methylglutaryl coenzyme A lyase in mice causes cardiomyopathy and a distinct pattern of acyl-coenzyme A-related biomarkers.
2022
Mol. Genet. Metab. 137, 257-264. PMID: 36228350
Yang, H., Wang, Y., Tang, M-C., Waters, P., Wang, S., Allard, P., Ryan, R.O., Nuyt, A-M., Paradis, P., Schiffrin, E.L., Furtos, A. and Mitchell, G.A.
Cardiolipin nanodisks confer protection against doxorubicin-induced mitochondrial dysfunction.
2022
BBA Biomembranes.1864, 183984; DOI: 10.1016/j.bbamem.2022.183984. PMID: 35724738
Fox, C.A., Romenskaia, I. Dagda, R.K. and Ryan, R.O.
Diversion of acetyl CoA to 3-methylglutaconic acid caused by discrete inborn errors of metabolism.
2022
Metabolites, 12, 377. PMCID: PMC9146172
Jones, D.E., Jennings, E.A. and Ryan, R.O.
Foam fractionation of a recombinant biosurfactant apolipoprotein.
2022
J. Biotechnol. 343, 25-31. PMCID: PMC8714704.
Lethcoe, K., Fox, C.A. and Ryan, R.O.
Lutein nanodisks protect retinal pigment epithelial cells from UV light induced damage.
2022
Front. Nanotechnol. 4:955022. PMCID: PMC9851610. doi: 10.3389/fnano.2022.955022
Moschetti, A., Fox, C.A., McGowen, S. and Ryan, R.O.
Role of non-enzymatic chemical reactions in 3-methylglutaconic aciduria
2022
FEBS J. 289, 2948-2958. PMCID: PMC9117401
Jones, D.E., Romenskaia, I., Kosma, D.K. and Ryan R.O.
Studies of the cardiolipin interactome.
2022
Prog. Lipid Res. 88, 101195 PMID: 36202313.
Fox, C.A. and Ryan, R.O.
Calcium-induced release of cytochrome c from cardiolipin nanodisks: implications for apoptosis
2021
BBA Biomembranes, 1863, 183722. PMCID: PMC8464532
Fox, C.A., Lethcoe, K., and Ryan, R.O.
Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes.
2021
Nanomedicine NBM, 37, 102439. PMCID: PMC8464493
Moschetti, A, Dagda, R.K. and Ryan, R.O.
Inborn errors of metabolism associated with 3-methylglutaconic aciduria.
2021
Clin. Chim. Acta. 522, 96-104. PMCID: PMC8464523
Jones, D.E., Klacking, E. and Ryan R.O.
Isomerization of 3-methylglutaconic acid.
2021
JIMD Reports, 58, 61-69. PMCID: PMC7932859
Jones, D.E., Ricker, J.D., Geary, L.M., Kosma, D.K. and Ryan R.O.
Reconstituted HDL as a therapeutic delivery device.
2021
BBA Mol. Cell Biol. Lipids, 1866, 159025. PMCID: PMC9336189
Fox, C.A., Moschetti, A. and Ryan R.O.
trans-3-methylglutaconyl CoA isomerization-dependent protein acylation.
2021
Biochem. Biophys. Res. Commun. 534, 261-265. PMCID: PMC7785636
Young, R., Jones, D.E., Diacovich, L., Witkowski, A. and Ryan, R.O.
3-methylglutaric acid in mitochondrial energy metabolism.
2020
Clin. Chim. Acta. 502, 233-239. PMCID: PMC6994337
Jones, D.E., Perez, L. and Ryan, R.O.
Dye binding assay reveals doxorubicin preference for DNA versus cardiolipin
2020
Anal. Biochem. 594, 113617. PMCID: PMC7058507
Fox, C.A. and Ryan R.O.
Isomerization of trans-3-methylglutaconic acid
2020
JIMD Reports. 2020;1-9
Dylan E. Jones, J. David Ricker, Laina M. Geary, Dylan K. Kosma, Robert O. Ryan
Effect of curcumin on amyloid-like aggregates generated from methionine-oxidized apolipoprotein A-I.
2018
FEBS Open Bio. 2018 Jan 10;8(2):302-310.
Krishnamo01thy A, Tavoosi N, Chan GKL, Liu J, Ren G, Cavigiolio G and Ryan RO
Evaluation of cardiolipin nanodisks as lipid replacement therapy for Barth syndrome. J Biomed Res. 32
2018
J Biomed Res. 32(2): 107–112.
Ikon N, Hsu FF, Shearer J, Forte TM, Ryan RO
Sphingadienes show therapeutic efficacy in neuroblastoma in vitro and in vivo by targeting the AKT signaling pathway.
2018
Invest New Drugs. 36(5):743-754
Zhao P, Aguilar AE, Lee JY, Paul LA, Suh JH, Puri L, Zhang M, Beckstead J, Witkowski A, Ryan RO, Saba JD
Barth Syndrome: Connecting Cardiolipin to Cardiomyopathy.
2017
Lipids. 2017 Feb;52(2):99-108.
Ikon N, Ryan RO.
Cardiolipin and mitochondrial cristae organization.
2017
Biochim Biophys Acta. 2017 Jun;1859(6):1156-1163.
Ikon N, Ryan RO.
Apolipoprotein A-V gene therapy for disease prevention / treatment: a critical analysis.
2016
J Biomed Res. 2016 Mar;30(2):88-93.
Forte TM, Sharma V, Ryan RO
Apolipoprotein A-V is present in bile and its secretion increases with lipid absorption in Sprague-Dawley rats.
2015
Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1;309(11):G918-25
Zhang LS, Sato H, Yang Q, Ryan RO, Wang DQ, Howles PN, Tso P.
Apolipoprotein A5: Extracellular and Intracellular Roles in Triglyceride Metabolism.
2015
Curr Drug Targets. 2015;16(12):1274-80. Review.
Forte TM, Ryan RO.
Metabolic annotation of 2-ethylhydracrylic acid.
2015
Clin Chim Acta. 2015 Aug 25;448:91-7
Ryan RO
Curcumin homing to the nucleolus: mechanism for initiation of an apoptotic program.
2014
J Nutr Biochem. 2014 Nov;25(11):1117-1123.
Ghosh M, Ryan RO.