claudia rueckert

Claudia Rückert

Assistant Professor she/her


Our main research interest is in virus-vector interactions. Arthropod vectors of human pathogens include mosquitoes and ticks. We focus mainly on mosquito antiviral responses with the aim of identifying targets for arbovirus transmission control. Further projects will focus on mosquito biology, vector control and molecular biology of viruses that are transmitted by arthropod vectors. We are also interested in virus-tick interactions.


  • BCH 405/605 Molecular Biology in the Spring semester
  • BCH 790 Biochemistry Seminar in the Spring and Fall semester


  • B.S., University of Heidelberg, Germany, 2008
  • M.S., University of Heidelberg, Germany, 2010
  • Ph.D., University of Edinburgh, UK, 2014


Publications are listed below.


Elucidating the role of dsRNA sensing and Toll6 in antiviral responses of Culex quinquefasciatus cells.


Front Cell Infect Microbiol

Prince BC, Chan K, Rückert C.

Evaluation of Vector-Enabled Xenosurveillance in Rural Guatemala.


Am J Trop Med Hyg.

McMinn RJ, Chacon A, Rückert C, Scorza V, Young MC, Worthington D, Lamb MM, Medrano RE, Harris EK, Arias K, Lopez MR, Asturias EJ, Foy BD, Stenglein MD, Olson D, Ebel GD.

Intracellular Diversity of WNV within Circulating Avian Peripheral Blood Mononuclear Cells Reveals Host-Dependent Patterns of Polyinfection



Talmi-Frank D, Byas AD, Murrieta R, Weger-Lucarelli J, Rückert C, Gallichotte EN, Yoshimoto JA, Allen C, Bosco-Lauth AM, Graham B, Felix TA, Brault AC, Ebel GD.

Recognition of Arboviruses by the Mosquito Immune System.



Prince BC, Walsh E, Torres TZB, Rückert C.

The Incompetence of Mosquitoes-Can Zika Virus Be Adapted To Infect Culex tarsalis Cells?



Gallichotte EN, Samaras D, Murrieta RA, Sexton NR, Robison A, Young MC, Byas AD, Ebel GD, Rückert C.

Impact of extrinsic incubation temperature on natural selection during Zika virus infection of Aedes aegypti and Aedes albopictus.


PLoS Pathogens

Murrieta RA, Garcia-Luna SM, Murrieta DJ, Halladay G, Young MC, Fauver JR, Gendernalik A, Weger-Lucarelli J, Rückert C, Ebel GD.

Arbovirus co-infection and co-transmission: a neglected public health concern? Unsolved Mystery


PLoS Biology.

C. B. F. Vogels, C. Rückert, S. M. Cavany, T. A. Perkins, G. D. Ebel, N. D. Grubaugh

Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses



K. S. Carpentier, B. J. Davenport, K. C. Haist, M. K. McCarthy, N. A. May, A. Robison, C. Rückert, G. D. Ebel, and T. E. Morrison.

Profiling of small RNA responses of Culex cells and mosquitoes during acute and persistent virus infection.


Insect Biochemistry and Molecular Biology. 2019;

C. Rückert, A. N. Prasad, A. Robison, N. D. Grubaugh, J. Weger-Lucarelli, G. D. Ebel

Adventitious viruses persistently infect three commonly used mosquito cell lines.


Virology. 2018;

J. Weger-Lucarelli, C. Rückert, N. D. Grubaugh, M. J. Misencik, P. M. Armstrong, M. D. Stenglein, G. D. Ebel, D. Brackney.

How do virus-mosquito interactions lead to viral emergence?


Trends in Parasitology. 2018;

C. Rückert, G. D. Ebel

Impact of simultaneous exposure to arboviruses on infection and transmission by Aedes aegypti mosquitoes.


Nature Communications. 2017;

C. Rückert, J. Weger-Lucarelli, S. M. Garcia-Luna, M. C. Young, A. D. Byas, R.A. Murrieta, J. R. Fauver, G. D. Ebel

Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus is dependent on salivary gland infection and escape barriers.


PLoS NTD. 2018;

S. M. Garcia-Luna, J. Weger-Lucarelli, C. Rückert, R. A Murrieta, M. C. Young, A. D. Byas, J. R. Fauver, R. Perera, A. E. Flores-Suarez, G. Ponce-Garcia, A. D. Rodriguez, G. D. Ebel, W. C. Black IV

Mosquitoes transmit unique West Nile virus populations during each feeding episode.


Cell Reports. 2017;

N. D. Grubaugh, J. R. Fauver, C. Rückert, J. Weger-Lucarelli, S. Garcia-Luna, R. A. Murrieta, A. Gendernalik, D. R. Smith, D. E. Brackney, G. D. Ebel

The influence of genetic bottlenecks, RNA interference-mediated diversification, and selective constraint on the evolution of a tick-borne virus.


Virus evolution.

N. D. Grubaugh, C. Rückert, P. M. Armstrong, A. Bransfield, J. Anderson, G. D. Ebel, D. E. Brackney

Antiviral responses of arthropod vectors: an update on recent advances’ Review article,



C. Rückert, L. Bell-Sakyi, J. K. Fazakerley & R. Fragkoudis

Co-infection of tick cell lines affects replication of intracellular bacterial and viral pathogens


Ticks and Tick-borne Diseases;

A. Moniuszko, C. Rückert, M. P. Alberdi, G. Barry, B. Stevenson, J. K. Fazakerley, A. Kohl & L. Bell-Sakyi