claudia rueckert

Claudia Rückert

Assistant Professor she/her

Summary

Rückert's main research interest is virus-vector interactions. She is establishing a research program focusing on mosquito antiviral responses with the aim of identifying targets for arbovirus transmission control. Further projects will focus on mosquito biology, vector control and molecular biology of viruses that are transmitted by arthropod vectors. I am also interested in virus-tick interactions.

Courses

  • BCH/BIOL 405/605 Molecular Biology in the Spring semester and BCH790 Biochemistry Seminar in the Fall semester.

Education

  • Gymnasium Tauberbischofsheim, Germany, 2005
  • BS Biology, University of Heidelberg, Germany, 2008
  • MS Molecular Biosciences, University of Heidelberg, Germany, 2010
  • PhD Virology, University of Edinburgh, UK, 2014

Publications

Journals

Arbovirus co-infection and co-transmission: a neglected public health concern? Unsolved Mystery

2019

PLoS Biology. doi.org/10.1371/journal.pbio.3000130.

C. B. F. Vogels, C. Rückert, S. M. Cavany, T. A. Perkins, G. D. Ebel, N. D. Grubaugh

Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses

2019

eLife

K. S. Carpentier, B. J. Davenport, K. C. Haist, M. K. McCarthy, N. A. May, A. Robison, C. Rückert, G. D. Ebel, and T. E. Morrison.

Profiling of small RNA responses of Culex cells and mosquitoes during acute and persistent virus infection.

2019

Insect Biochemistry and Molecular Biology. 2019; doi.org/10.1016/j.ibmb.2019.04.008

C. Rückert, A. N. Prasad, A. Robison, N. D. Grubaugh, J. Weger-Lucarelli, G. D. Ebel

Adventitious viruses persistently infect three commonly used mosquito cell lines.

2018

Virology. 2018; doi.org/10.1016/j.virol.2018.06.007

J. Weger-Lucarelli, C. Rückert, N. D. Grubaugh, M. J. Misencik, P. M. Armstrong, M. D. Stenglein, G. D. Ebel, D. Brackney.

How do virus-mosquito interactions lead to viral emergence?

2018

Trends in Parasitology. 2018; doi.org/10.1016/j.pt.2017.12.004

C. Rückert, G. D. Ebel

Impact of simultaneous exposure to arboviruses on infection and transmission by Aedes aegypti mosquitoes.

2018

Nature Communications. 2017; doi.org/10.1038/NCOMMS15412

C. Rückert, J. Weger-Lucarelli, S. M. Garcia-Luna, M. C. Young, A. D. Byas, R.A. Murrieta, J. R. Fauver, G. D. Ebel

Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus is dependent on salivary gland infection and escape barriers.

2018

PLoS NTD. 2018; doi.org/10.1371/journal.pntd.0006599.

S. M. Garcia-Luna, J. Weger-Lucarelli, C. Rückert, R. A Murrieta, M. C. Young, A. D. Byas, J. R. Fauver, R. Perera, A. E. Flores-Suarez, G. Ponce-Garcia, A. D. Rodriguez, G. D. Ebel, W. C. Black IV

Mosquitoes transmit unique West Nile virus populations during each feeding episode.

2017

Cell Reports. 2017; doi.org/10.1016/j.celrep.2017.03.076.

N. D. Grubaugh, J. R. Fauver, C. Rückert, J. Weger-Lucarelli, S. Garcia-Luna, R. A. Murrieta, A. Gendernalik, D. R. Smith, D. E. Brackney, G. D. Ebel

The influence of genetic bottlenecks, RNA interference-mediated diversification, and selective constraint on the evolution of a tick-borne virus.

2016

Virus evolution. doi.org/10.1093/ve/vew033.

N. D. Grubaugh, C. Rückert, P. M. Armstrong, A. Bransfield, J. Anderson, G. D. Ebel, D. E. Brackney

Antiviral responses of arthropod vectors: an update on recent advances’ Review article,

2014

VirusDisease, doi.org/10.1007/s13337-014-0217-9.

C. Rückert, L. Bell-Sakyi, J. K. Fazakerley & R. Fragkoudis

Co-infection of tick cell lines affects replication of intracellular bacterial and viral pathogens

2014

Ticks and Tick-borne Diseases; doi.org/10.1016/j.ttbdis.2014.01.010.

A. Moniuszko, C. Rückert, M. P. Alberdi, G. Barry, B. Stevenson, J. K. Fazakerley, A. Kohl & L. Bell-Sakyi