Silvia Stan

Silvia Stan

Assistant Professor


Nutrition and Cancer Prevention; Mechanisms of action of food bioactive compounds; Breast cancer and pancreatic cancer chemoprevention.


Ph.D., Oregon State University



Diallyl trisulfide, a chemopreventive agent from Allium vegetables, inhibits alpha-secretases in breast cancer cells.


Biochemical and Biophysical Research Communications 484(4): 833-838.

Kiesel V.A., Stan S.D.

Dietary bioactive diallyl trisulfide in cancer prevention and treatment.


International Journal of Molecular Sciences 18(8): E1645.

Puccinelli M.T., Stan S.D.

Phenethyl isothiocyanate inhibits proliferation and induces apoptosis in pancreatic cancer cells in vitro and in a MIAPaca2 xenograft animal model.


Nutrition and Cancer 66(4): 747-755.

Stan S.D., Singh S.V., Whitcomb D.C., Brand R.E.

Chemoprevention strategies for pancreatic cancer.


Nature Reviews Gastroenterology and Hepatology 7(6): 347-356.

Stan S.D., Singh S.V., Brand R.E.

Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells.


Cancer Research 69(5): 2117-2125.

Singh S.V., Warin R., Xiao D., Powolny A.A., Stan S.D., Arlotti J.A., Zeng Y., Hahm E.R., Marynowski S.W., Bommareddy A., Desai D., Amin S., Parise R.A., Beumer J.H., Chambers W.H.

Transcriptional repression and inhibition of nuclear translocation of androgen receptor by diallyl trisulfide in human prostate cancer cells.


Clinical Cancer Research 15(15): 4895-4903.

Stan S.D., Singh S.V.

Ayurvedic medicine constituent Withaferin A causes G2 and M phase cell cycle arrest in human breast cancer cells.


Nutrition and Cancer 60(S1): 51-60.

Stan S.D., Zeng Y., Singh S.V.

Bioactive food components and cancer risk reduction.


Journal of Cellular Biochemistry 104(1): 339-356.

Stan S.D., Kar S., Stoner G.D., Singh S.V.

Garlic constituent diallyl trisulfide prevents development of poorly differentiated prostate cancer and pulmonary metastasis multiplicity in TRAMP mice.


Cancer Research 68(22): 9503-9511.

Singh S.V., Powolny A.A., Stan S.D., Xiao D., Arlotti J.A., Warin R., Hahm E.R., Marynowski S.W., Bommareddy A., Pottter D.M., Dhir R.

Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.


Cancer Research 68(18): 7661-7669.

Stan S.D., Hahm E.R., Warin R., Singh S.V.

Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic.


Molecular Cancer Therapeutics 6(4): 1249-1261.

Herman-Antosiewicz A., Stan S.D., Hahm E.R., Xiao D., Singh S.V.