|Contact Information for Nevada Proteomics Center|
|Phone||(775) 784-6337: 2-D Gels|
|Phone||(775) 784-1590: Mass Spectrometry|
|Location||School of Medicine
Manville Medical Building, Rooms 15-17, MS 0330
|Address||1664 N. Virginia Street
Reno, NV 89557-MS 0330
Two-dimensional gel electrophoresis is a powerful technique for separating and visualizing proteins in a biological sample.
Despite many advances in alternative techniques, such as 2-D HLPC, it is still the most commonly used proteomics separation method. However, it is not a perfect technique for all proteins. Very large or hydrophobic proteins or proteins present in very minute quantities are often not seen on gels. These can be the proteins that are most interesting. Various approaches can be used to aid in the detection of these proteins.