CURRICULUM VITAE

Gary K. Shen, M.D.

Department Address

 

EDUCATION AND DEGREES:

University of California, Berkeley

  • Regent’s Scholar
  • Degree: BA, Physics, May 1984

    • University of Rochester

  • School of Medicine and Dentistry, Rochester, New York
  • Degree: MD, May 1988

     

    POST GRADUATE TRAINING:

    Internship/Residency:

  • University of Arizona - Tucson Hospitals
  • Surgery Residency Program, 1988 - 1995
  • Chairman, Department of Surgery: Bruce E. Jarrell, M.D.
  • Residency Program Director: Charles W. Putnam, M.D.

    • Fellowship:

  • Multi-Organ Transplant Fellowship
  • Stanford University Medical Center, 1995 - 1996
  • Director: Donald C. Dafoe, M.D.

    •  

    APPOINTMENTS
    March 2000
    		University of Nevada School of Medicine
    Associate Professor of Surgery
    Director of Transplantation
    July 1996 - February 2000
    		Albany Medical College, Albany, New York
    Assistant Professor of Surgery
    July 1996 - current
    		Albany Medical Center
    Staff Surgeon
    April 1997 - current
    		St. Peter’s Hospital
    Staff Surgeon
    April 1997 - current
    		Albany Memorial Hospital
    Staff Surgeon

    Post-graduate Research
    1990 - 1992
    		Department of Surgery and Research Services
    Veteran Affairs Medical Center, Tucson, Arizona
    Preceptors:Charles F. Zukoski, M.D. and David W. Montgomery, Ph.D.
    Research Areas:
  • Immune function of pituitary hormones
  • Immunosuppressive cyclic peptides
  • Lymphokine effects on the neuroendocrine system


    • Publications

    1. Failure of ganciclovir prophylaxis to completely eradicate CMV disease in renal transplant recipients treated with intense anti-rejection immunotherapy. Isenberg AL, Shen GK, Singh TP, Hahn A, Conti DJ. Accepted for publication, Clin Transplant.
    2. Causes of long-term renal allograft failure: no chronic rejection at three years. Shen GK, Isenberg Al, Singh TP, Hahn A, Conti DJ. Transplant Proc 1998: 30, 1205-1206.
    3. Shen GK, Salvatierra Jr O, Dafoe DC, and Alfrey EJ. Use of split horseshoe kidney for transplantation. Surgery 1998, 123: 475-477.
    4. Shen GK, Alfrey EJ, Knoppel CL, Dafoe DC, and Scandling JD. Eradication of cytomegalovirus reactivation disease using high dose acyclovir and targeted ganciclovir in kidney and kidney/pancreas transplantation. Transplantation 1997, 64: 931-933.
    5. Conti DJ, Shen GK, Singh T, Isenberg A, and Freed BM. Ganciclovir prophylaxis of cytomegalovirus disease. Transplant Proc 1997, 29: 804-806.
    6. Lee CM, Scandling JD, Shen GK, Salvatierra O, Dafoe DC, and Alfrey EJ. The kidneys that nobody wanted: Support for the utilization of expanded criteria donors. Transplantation 1996, 62: 1832-1841.
    7. Shen GK, Tsen AC, Hunter GC, Ghory MJ, and Rappaport W. Surgical treatment of symptomatic biliary stones in patients with cystic fibrosis. Am Surg 1995, 61: 814-819.
    8. Montgomery DW, Shen GK, Ulrich ED, and Zukoski CF. Immunomodulation by didemnins: invertebrate marine natural products. Ann NY Acad Sci 1994, 712: 301-304.
    9. Montgomery DW, Shen GK, Ulrich ED, Steiner LL, Parrish PR, and Zukoski CF. Human thymocytes express a prolactin-like messenger ribonucleic acid and synthesize bioactive prolactin-like proteins. Endocrinology 1992, 131: 3019-3026.
    10. Shen GK, Montgomery DW, Ulrich ED, Mahoney KR, and Zukoski CF. Up-regulation of prolactin gene expression and feedback modulation of lymphocyte proliferation during acute allograft rejection. Surgery 1992, 112: 387-394.
    11. Shen GK, Zukoski CF, and Montgomery DW. A specific binding site in Nb2 node lymphoma cells mediates the effects of didemnin B, an immunosuppressive cyclic peptide. Int J Immunopharm 1992, 14: 63-73.
    12. Shen GK, and Rappaport W. Control of intra-abdominal hemorrhage with temporary packing. Surg Gynecol Obstet 1992, 174: 411-413.
    13. Shen GK, Wong R, Daller J, Melcer S, Tsen A, Awtrey S, and Rappaport W. Does the retrocecal position of the vermiform appendix alter the clinical course of acute appendicitis? A prospective analysis. Arch Surg 1991, 126: 569-570.
    14. Shen GK, Carnahan W, and Rappaport W. The varied presentation of retroperitoneal appendicitis. Contemp Surg 1990, 37: 9-13.


    Abstracts

    1. A novel intervention to increase organ donation rates. Conti DJ, Singh TP, Shen GK, Taft F. Submitted for presentation to the American Society of Transplantation, May, 2000.
    2. Effect of cytokine gene promoter polymorphisms on renal allograft outcome. Hahn AB, Kasten-Jolly JC, Constantino DM, Singh TP, Shen GK, Conti DJ. The American Society of Histocompatibility and Immunogenetics, New Orleans, October 1999.
    3. Effect of cytokine gene promoter polymorphisms on pre-transplant alloantibody production. Hahn AB, Kasten-Jolly JC, Constantino DM, Allen M, Singh TP, Shen GK, Conti DJ. The American Society of Histocompatibility and Immunogenetics, New Orleans, October 1999.
    4. Increasing living donor pool for renal transplantation: paired donation vs. cadaver exchange. Shen GK, Singh TP, Funk D, Conti DJ. The American Society of Transplantation, Chicago, May 1999.
    5. Early acute rejection and late graft loss: an analysis of paired cadaver kidneys. Conti DJ, Isenberg AI, Hahn A, Shen GK, and Singh TP. The American Society of Transplant Surgeons, Chicago, May 1998.
    6. Failure of ganciclovir prophylaxis of CMV disease in immunologic high-risk recipients. Isenberg AI, Shen GK, Singh TP, Hahn A, and Conti DJ. The Surgical Infection Society, New York City, May 1998.
    7. Shen GK, Isenberg AL, Singh TP, Freed BM, Lempert N, and Conti DJ. Causes of long term renal allograft failure- no chronic rejection at three years. The International Congress on Immunosuppression, Orlando, December 1997.
    8. Isenberg A, Singh TP, Shen GK, Freed B, and Conti DJ. Selective Cellcept therapy in high-risk renal transplant recipients. The International Congress on Immunosuppression, Orlando, December 1997.
    9. Conti DJ, Shen GK, Isenberg A, and Singh TP. Failure of ganciclovir prophylaxis of primary CMV disease in immunologic high-risk recipients. The International Congress on Immunosuppression, Orlando, December 1997.
    10. Singh TP, Isenberg A, Shen GK, Freed BM, and Conti DJ. Improved graft survival in retransplant recipients: an analysis of paired cadaver kidneys. American Society of Transplant Surgeons, Chicago, May 1997.
    11. Lee CM, Scandling JD, Shen GK, Knoppel CL, Dafoe DC, and Alfrey EJ. The kidneys that nobody wanted. American Society of Transplant Physicians, Dallas, May, 1996.
    12. Shen GK, Alfrey EJ, Knoppel CL, Dafoe DC, and Scandling JD. Eradication of CMV reactivation disease: prophylaxis using high dose acyclovir and preemptive ganciclovir in kidney and kidney/pancreas transplantation. American Society of Transplant Physicians, Dallas, May, 1996.
    13. Shen GK, Alfrey EJ, and Dafoe DC. Use of dual cadaveric kidneys for transplant into a single recipient. Western Association of Transplant Surgeons, Seattle, February, 1996.
    14. Montgomery DW, Shen GK, Ulrich ED, and Zukoski CF. Immunomodulation by didemnins: invertebrate marine natural products. New York Academy of Sciences, New York, May, 1993.
    15. Shen GK, Montgomery DW, and Zukoski CF. Up-regulation of prolactin gene expression during allograft rejection: possible role of IL-1 and IL-6. First prize, Davis & Geck resident research award, University of Arizona, May, 1992,
    16. Shen GK, Montgomery DW, Ulrich ED, Mahoney KR, and Zukoski CF. Up-regulation of prolactin gene expression and feedback modulation of lymphocyte proliferation during acute allograft rejection. Society of University Surgeons, Cincinnati, February, 1992.
    17. Shen GK, Zukoski CF, and Montgomery DW. Identification of a binding site for didemnin B, an immunosuppressive peptide, in normal lymphocytes and Nb2 lymphoma cells. First prize, Davis & Geck resident research award, University of Arizona, May, 1991.
    18. Shen GK, Allen RC, Hunter GC, Zuniga RE, and Rappaport W. Peri-operative myocardial infarction in patients undergoing non-vascular procedures. Southwestern Surgical Congress, Tucson, April, 1994.
    19. Shen GK, Montgomery DW, and Zukoski CF. Identification of didemnin B binding sites on Nb2 node lymphoma cells. Federation of American Society of Experimental Biology, Atlanta, April, 1991.
    20. Shen GK, and Rappaport W. Control of non-hepatic intra-abdominal hemorrhage with temporary packing. Southwestern Surgical Congress, Las Vegas, April, 1991.


    Invited Forums

    1. The 1999 Upstate New York Transplant Meeting, Syracuse, Oct 1999: Lymphoceles after renal transplantation.
    2. Endocrinology grand round, Albany Medical Center, March 1999: Prospects for islet cell transplantation.
    3. Invited speaker, Nanking Medical Center, Nanking, China, January 1999: Current status of kidney and pancreas transplantation.
    4. Invited speaker, First Medical College, Chendu, China, January 1999: Organ procurement, distribution, and preservation in the United State.
    5. Nephrology grand round, Albany Medical Center, April 1998: Simultaneous pancreas kidney transplantation for diabetic patients with ESRD.
    6. Future Trends in Transplantation, Albany, NY, November 1997: Trends in pancreatic and islet cell transplant.
    7. CME course, Nathan Littore Hospital, Gloversville, NY, July 1997: Organ donation in the United States.
    8. Surgery grand round, Albany Memorial Hospital, Albany, NY, November 1996: Pancreas transplant: current status and updates.
    9. Phase III renal transplant advisory meeting, Boston, MA, May 1997: Prograf in renal transplantation.


    Research Protocols
    Principal Investigator
    		Fenoldopam for delayed graft function after renal transplantation, 1999.
    		Thermal dilution probe for monitoring renal blood flow after transplantation, 1998.
    		Abbott IMX Assay for Tacrolimus, 1996.
    Co-Investigator
    		An open label, randomized, multicenter study to evaluate the safety and efficacy of Zenapax in combination with Cellcept, corticosteroids and standard or reduced dose Prograf for the prevention of acute rejection in primary renal allograft recipients. 1999.
    		A clinical experience with Abbott cyclosporine in de novo renal transplant subjects, 1999.
    		A three-year, randomized, multicenter, double-blind, double-dummy, parallel group study of the efficacy and safety of SDZ RAD tablets versus mycophenolate mofetil as part of triple immunosuppressive therapy in de novo renal transplant recipients, 1998.
    		A comparative study of the effect and equivalence of sirolimus oral liquid versus sirolimus tablets, administered concomitantly with cyclosporine and corticosteroids in renal allograft recipients, 1997.
    		Oral valaciclovir safety, pharmacokinetics and suppression of cytomegalovirus infection and disease in renal allograft recipients, 1997.
    		A double-blind, comparative study of the effect of two dose levels of sirolimus versus azathioprine, administered concomitantly with standard immunosuppressive therapy in renal allograft recipients, 1996.
    		A randomized, double-blind comparative study of safety of intravenous mycophenolate mofetil and oral mycophenolate mofetil in renal transplant recipients in the immediate post-operative period, 1996.
    		A 6-day open-label pharmacokinetics bioavailability evaluation of mycophenolic acid when switching from intravenous mycophenolate mofetil to oral mycophenolate mofetil in renal transplant recipients in the immediate post-operative period, 1996.


    Committees
    1997 - 1999
    		Kidney/pancreas committee region 9 representative, the United Network of Organ Sharing
    1997 - 2000
    		Pharmacy and Therapeutics committee, Albany Medical Center
    1996 - 2000
    		Antibiotics Committee, Albany Medical Center
    1998 - 2000
    		Transplant Quality Improvement Team, Albany Medical Center

    Organizations
    1996 - current
    		American Society of Transplant Surgeons
    1999
    		Fellow of American College of Surgeons
    1999
    		American Society of Transplantation
    1988
    		American Medical Association

    Certifications
    		Certification, American Board of Surgery


    		State of California medical license


    		State of New York medical license


    		State of Nevada medical license





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