Scholar: Conrad Kiyoshi
Faculty Mentor: Dr. Patricia Berninsone
Research Topic: "The Role of the Protein Calnexin in the Secretory Pathway of Caenorhabditis Elegans: an RNAi Approach"
Abstract: This study will attempt to discern the functional necessity of the protein chaperone calnexin in Caenorhabditis elegans, in relation to the secretory pathway. In C.elegans, mutations of calnexin, and its homologue calreticulin, do not seem essential as the organisms and their progeny are viable in unstressed conditions. The study will introduce cell stress, such as removing the p24 gene which is involved in protein trafficking, by RNAi feeding to determine if there is some redundancy in function between the two chaperones, or if calnexin has a novel function in protein selection and trafficking.
Earned Baccalaureate Degree: Spring 2008
Doctoral Program Update: Accepted into a PhD program in Biomedical Sciences at Ohio State University.