James L. Kenyon
Department: Physiology & Cell Biology
Academic Unit: School of Medicine
Professional degrees (Degree, year, Institution): Ph.D. 1977 University of Vermont
Mail Stop: 352
Sensory neurons convert stimuli such as touch, heat, or chemicals into electrical signals that are interpreted by the nervous system as sensation. Our lab investigates the mechanisms by which these neurons set their sensitivity with particular attention to those neurons responsible for generating pain signals. We are currently studying the control of intracellular calcium, a key signaling mechanism, as one important mechanism.
Kenyon, J. L. and McHugh, J. M. An Excel-based model of Ca2+ diffusion and fluorescence measurements of Ca2+ in a spherical cell. Biophysical Journal 18a, 577-Pos. 2004. Abstract
Angermann JE, Sanguinetti AR, Kenyon JL, Leblanc N and Greenwood IA. Mechanism of the inhibition of Ca2+-activated Cl- currents by phosphorylation in pulmonary arterial smooth muscle cells. J Gen Physiol 128: 73-87, 2006.
Bayguinov O, Ward SM, Kenyon JL and Sanders KM. Voltage-gated Ca2+ currents are necessary for slow-wave propagation in the canine gastric antrum. Am J Physiol Cell Physiol 293: C1645-C1659, 2007.
Kang SH, Carl A, McHugh JM, Goff HR and Kenyon JL. Roles of mitochondria and temperature in the control of intracellular calcium in adult rat sensory neurons. Cell Calcium 43: 388-404, 2008
Britton FC, Leblanc N and Kenyon JL. Calcium-Activated Chloride Channels. In: Physiology and Pathology of Chloride Transporters and Channels in the Nervous System from Molecules to Diseases, edited by Alvarez-Leefmans FJ and Delpire E. San Diego, CA: Elsevier- Academic Press, 2009.
Faculty by research area
- Mastick, C
- Mastick C.
- Mastick G.
- Van der Linden
- von Bartheld
- von Bartheld