Glycosylation Status of Proteins
The goal of our research is to gain insight into how the correct assembly of glycans is regulated and how the glycosylation status of proteins relates with their trafficking and –ultimately - with their biological activities in the context of a multicellular organism. To address these questions, we are using the nematode Caenorhabditis elegans, a genetically tractable model organism.
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Infectious Microbes
The focus of the Aucoin and Kozel labs is to identify antigens that are shed by microbes during infection. These antigens are then targeted with monoclonal antibodies for diagnostic and therapeutic applications. Shown above is a fluorescently labeled monoclonal antibody binding to a Burkholderia species. This bacterium causes significant morbidity and mortality in SE Asia.
The Diagnostic Discovery Lab
Migrating Neurons
The migration of neurons is tightly controlled by guidance cues, secreted proteins that signal through cell surface receptors.
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RNA molecules that regulate gene expression
The Yan lab explores the recently discovered world of regulatory RNAs, and their role in epigenetics. The image shows cross sections of the seminiferous tubule containing developing spermatogenic cells in the mouse testis. Nuclei are stained with DAPI (blue) and cytoplasmic ribonucleoprotein particles are in yellow/green.
Read More about Wei Yan's Researc0Why MB?
The Molecular Biosciences Interdisciplinary Program at the University of Nevada at Reno provides an integrated course of study for students seeking a PhD or MS degree in biomolecular-related research. Over 60 participating Faculty members are drawn from nine different departments from across the campus in the Colleges of Agriculture, Biotechnology and Natural Resources, Medicine, and Science. The program provides a supportive environment for over 100 graduate students with excellent opportunities in a broad range of biological and biomedical research areas, including biochemistry, bioinformatics, cancer biology, cardiovascular research, cell biology, gametogenesis and fertility, functional genomics, hormones, immunology, infectious diseases, insect biochemistry, insect molecular genetics, neuroscience, metabolic regulation, metabolomics, microbiology, microbial ecology, nutrition, regulation of gene expression, pathology, protein structure-function, plant biochemistry, plant molecular genetics, proteomics, signal transduction, smooth muscle biology, stem cell biology, and virology.