Post Approval Monitoring (PAM)
The recent update (6/2010) of the Guide for the Care and Use of Laboratory Animals has included the requirement for the facility to have a Post Approval Monitoring (PAM) Program for the facilities’ protocols that have been approved through the Institutional Animal Care and Use Committee (IACUC). This has been discussed with our EHS group to allow efficiencies for the Labs in these reviews. Ideally we will be conducting both the lab safety review and the PAM review simultaneously as there is much overlap. The occupational health and safety programs are a dual responsibility between the IACUC and EHS and there is good agreement between the departments on this approach.
The PAM program has a defined checklist that will be followed for each visit. Visits were prioritized by the USDA Pain Category stated in the IACUC protocol starting with E’s, then D’s, then C’s. The goal is to review all the E’s, most of the D’s and approximately 10% of the C’s annually. Visits will be announced to the labs at least one week in advance. Checklist results and documented findings will be kept with EHS, a summary of the visit will be forwarded to the IACUC. The IACUC committee at regularly scheduled meetings, during the dedicated time for safety discussions, will review and discuss the summary reports at each meeting. Follow up reviews from the PAM committee to the IACUC as needed will be scheduled.
If there are deficiencies found at the PAM visits the type of deficiency will determine the lab’s needed response(s). The lab will need to respond to the PAM visitors/IACUC in a timely fashion as required by the visitors. If this is not done the IACUC will determine if the lab may continue to work on the designated protocol(s). Concerns found through the PAM process and vetted by the IACUC, will be shared with the department chair, the dean of the school, and the VP of Research.